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| Silva, Vanessa Carla Lima da; Silva, Francine Maria de França; Meunier, Isabelle Maria Jacqueline; Silva, Tânia Maria Sarmento da; Silva Júnior, Valdemiro Amaro da; Maia, Frederico Celso Lyra. |
| Teratogenicity and developmental abnormalities in the offspring of female rats that ingested ethanol extract of Neem plants during pregnancy and lactation period were assessed. Twenty-four female Wistar rats were randomly distributed in control group and in three experimental groups and treated during the 4th, 5th, and 6th day of pregnancy. After birth, the lactating females received, by gavage, 65, 135 and 200 mg kg-1 of Neem ethanol extract, during 15 days. Results show, there was no significant difference in body mass index of neonatal rats in the 4 groups evaluated, whereas mean rate of offspring survival was 79.4%. Hair growth, incisor teeth eruption, ear detachment, eyelid opening, and spontaneous ambulation were similar for all groups. Likewise,... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Morfologia e toxicologia medicinal plant; Reproduction; Teratogenicity; Physical development; Rodents Morfologia animal e Toxicologia. |
| Ano: 2015 |
URL: http://periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/24976 |
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| Silva, Alluanan Adelson do Nascimento; Oliveira, Jessica Santana de; Oliveira, Rodrigo Ribeiro de; Moraes, Sílvia Regina Arruda de; Silva Júnior, Valdemiro Amaro da; Melo, Elizabeth Neves de. |
| The goal of present study was to evaluate the effects of diabetes on quantitative parameters of Leydig cells. Twelve adults Wistar rats were divided in: 1) Diabetic Group (DG), which was induced by a single intraperitoneal injection of streptozotocin (60 mg kg-1 of body weight); and 2) Control Group (CG), which received citrate buffer intraperitoneal. After eight weeks of diabetic induction, the animals were weighted, anesthetized and testicles were removed and routinely processed to paraffin embedded. Body weight (40%) and testicular weight (18%) of diabetic rats were significantly lower than control group. Diabetic rats showed an increase in interstitial compartment but the tubular compartment did not differ. The individual volume of Leydig cells and... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: 2.00.00.00-6; 2.06.00.00-3 streptozotocin; Testes; Interstitial cells; Morphometry Morfofisiologia Animal. |
| Ano: 2014 |
URL: http://periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/22455 |
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