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Antiparasitic activity of chicory (Cichorium intybus) and its natural bioactive compounds in livestock: a review 21
Peña-Espinoza, Miguel; Valente, Angela H.; Thamsborg, Stig M.; Simonsen, Henrik T.; Boas, Ulrik; Enemark, Heidi L.; López-Muñoz, Rodrigo; Williams, Andrew R..
Increasing drug resistance in gastrointestinal (GI) parasites of livestock and concerns about chemical residues in animal products and the environment are driving the development of alternative control strategies that are less reliant on the use of synthetic drugs. An increasingly investigated approach is the use of bioactive forages with antiparasitic properties as part of the animal’s diet (nutraceuticals) or as potential sources of novel, natural parasiticides. Chicory (Cichorium intybus) is a multi-purpose crop and one of the most promising bioactive forages in temperate regions, and numerous in vivo trials have explored its potential against parasitic nematodes in livestock. However, it is unclear whether chicory can induce a direct and broad activity...
Tipo: Journal paper Palavras-chave: Production systems; Dairy cattle; Beef cattle; Sheep and goats; Health and welfare; Pigs.
Ano: 2018 URL: http://orgprints.org/33736/1/Pe%C3%B1a-Espinoza%20et%20al%202018.pdf
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Sesquiterpene lactone containing extracts from two cultivars of forage chicory (Cichorium intybus) show distinctive chemical profiles and in vitro activity against Ostertagia ostertagi 21
Peña-Espinoza, Miguel; Boas, Ulrik; Williams, Andrew R.; Thamsborg, Stig M.; Simonsen, Henrik T.; Enemark, Heidi L..
The study investigated direct anthelmintic effects of sesquiterpene lactones (SL)-containing extracts from forage chicory against free-living and parasitic stages of Ostertagia ostertagi. Freeze-dried leaves from chicory cultivars ‘Spadona’ and ‘Puna II’ were extracted using methanol/water. Total SL were further fractionated by solid-phase extraction and resulting extracts were characterised by high-performance liquid chromatography (HPLC). O. ostertagi eggs from faeces of mono-infected calves were hatched and L1 were used in a larval feeding inhibition assay (LFIA), while cultured L3 were used in a larval exsheathment inhibition assay (LEIA). Adult worms were immediately recovered after slaughter and used for motility inhibition assays (AMIA). Electron...
Tipo: Journal paper Palavras-chave: Crop husbandry; Health and welfare.
Ano: 2015 URL: http://orgprints.org/29425/1/Pe%C3%B1a-Espinoza%20et%20al%202015_IJPDDR%285%29.pdf
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