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	Provedor de dados Biocell (1) Autor DaMatta,Renato Augusto (1) Pacheco,Marcos Tadeu T. (1) Pacheco-Soares,Cristina (1) Soares da Silva,Newton (1) de CastroPazos,Marcelo (1) Palavra-chave Cell death (1) Laser (1) Photodynamic therapy (1) Phthalocyanines (1) Ultrastructure (1) Tipo do documento Info:eu-repo/semantics/article (1) Ano 2003 (1) País Argentina (1) Idioma Inglês (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 1 Primeira ... 1 ... Última Ultrastructural effects of two phthalocyanines in CHO-K1 and HeLa cells after laser irradiation Biocell de CastroPazos,Marcelo; Pacheco-Soares,Cristina; Soares da Silva,Newton; DaMatta,Renato Augusto; Pacheco,Marcos Tadeu T.. The effects of Photodynamic Therapy using 2nd generation photosensitizers have been widely investigated aiming clinical application treatment of solid neoplasms. In this work, ultrastructure changes caused by the action of two 2nd generation photosensitizers and laser irradiation on CHO-K1 and HeLa (neoplastic) cells were analyzed by transmission electron microscopy. Aluminum phthalocyanine chloride, aluminum phthalocyanine tetrasulfonate chloride and radiation from a semiconductor laser at a fluency of 0.5 J/cm² (Power=26mW; l=670nm) were used. The results showed induction of apoptosis. Such alterations where observed in HeLa but not in CHO-K1 cells after Aluminum phthalocyanine tetrasulfonate chloride (AlPcS4) photodynamic treatment. The Aluminum... Tipo: Info:eu-repo/semantics/article Palavras-chave: Photodynamic therapy; Phthalocyanines; Laser; Cell death; Ultrastructure. Ano: 2003 URL: http://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S0327-95452003000300001 Registros recuperados: 1 Primeira ... 1 ... Última

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