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| Benzaken,Adele Schwartz; Girade,Renato; Catapan,Elisa; Pereira,Gerson Fernando Mendes; Almeida,Elton Carlos de; Vivaldini,Simone; Fernandes,Neide; Razavi,Homie; Schmelzer,Jonathan; Ferraz,Maria Lucia; Ferreira,Paulo Roberto Abrão; Pessoa,Mario Guimarães; Martinelli,Ana; Souto,Francisco José Dutra; Walsh,Nick; Mendes-Correa,Maria Cassia. |
| ABSTRACT Introduction and aim: Hepatitis C is a key challenge to public health in Brazil. The objective of this paper was to describe the Brazilian strategy for hepatitis C to meet the 2030 elimination goal proposed by World Health Organization (WHO). Methods: A mathematical modeling approach was used to estimate the current HCV-infected Brazilian population, and to evaluate the relative costs of two different scenarios to address HCV disease burden in Brazil: (1) if no further changes are made to the HCV treatment program in Brazil; (2) where the WHO targets for 2030 elimination are met through diagnosis and treatment efforts peaking before 2024. Results: An anti-HCV prevalence of 0.53% was calculated for the total population. It was estimated that the... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Hepatitis C; Hepatitis C elimination; Hepatitis C disease burden; Brazil. |
| Ano: 2019 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702019000300182 |
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| Brito,Wagner Izidoro de; Alves-Junior,Eduardo Rodrigues; Oliveira,Rode Martinho de; Souto,Francisco José Dutra. |
| ABSTRACT Vaccination against the hepatitis A virus (HAV) administered in two doses has been used effectively in universal child immunization programs in several countries. A single-dose vaccination was adopted in some low-income countries in an attempt to reduce costs without losing effectiveness. In 2014, single-dose universal vaccination was introduced in Brazil for children aged two years. Since such strategy is still not universally accepted, its efficacy should be compared to the two-dose strategy. To assess the humoral response after the single-dose HAV vaccination schedule, a cross-sectional study was conducted in Primavera do Leste, in Mato Grosso state, Central Brazil, including 265 children vaccinated through the National Immunization Program.... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Hepatitis A vaccine; Single-dose schedule; Anti-HAV; Dried blood spot testing; Immunization programs. |
| Ano: 2018 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702018000300166 |
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