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Desmoplasic Ameloblastoma in Maxilla: Report of Case and Review of the Literature International Journal of Morphology
Alves,Pollianna Muniz; Pereira,Karuza Maria Alves; Vasconcelos,Marcelo Gadelha; Souza,Lélia Batista de; Queiroz,Lélia Maria Guedes de; Medeiros,Ana Myriam Costa.
The ameloblastoma is a benign neoplasm of epithelial odontogenic origin, slowly growing, locally invasive and it is the most common odontogenic tumor in the jaws. Histologically, various types have been described in literature. The desmoplastic variant is rare and characterized by difference in the typical findings of ameloblastoma, including localization, radiographic and histological features. The purpose of this article is to report a case of desmoplastic ameloblastoma in the left maxilla, and review of relevant literature, emphasizing peculiar aspects of this unusual lesion.
Tipo: Journal article Palavras-chave: Ameloblastoma; Desmoplastic Ameloblastoma; Odontogenic tumours.
Ano: 2008 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022008000200003
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Inmunohistochemical Expression of PCNA, p53 and bcl-2 in Pleomorphic Adenomas International Journal of Morphology
Gordón-Núñez,Manuel Antonio; Godoy,Gustavo Pina; Soares,Rosilene Calazans; Souza,Lélia Batista de; Freitas,Roseana de Almeida; Queiroz,Lélia María Guedes.
The aim of the study was to determine the immunohistochemical expression of the PCNA, p53 and bcl-2 proteins in pleomorphic adenomas.onineteen specimens of pleomorphic adenomas were selected for analysis by the streptavidin-biotin-peroxidase method with antibodies againstp53, PCNA and bcl-2 proteins. It was observedweak labeling for p53 in 12 cases (63.1%) andforPCNA in 8 (42.1%). With respect to the bcl-2 labeling index,ono expression of this protein was detected in 12 cases, corresponding to 63.1% of the sample. Based on these findings, it was concluded that p53 and PCNA can favor the proliferative activity of pleomorphic adenomas, whereas bcl-2 probably doesonot effectively particípate in the pathogenesis of this tumor.
Tipo: Journal article Palavras-chave: Pleomorphic adenoma; Salivary gland tumour; P53; PCNA; Bcl-2.
Ano: 2008 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022008000300010
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