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Souza,V.A.U.F.; Sumita,L.M.; Freire,W.; Sato,H.K.; Grandi,J.L.; Pierrotti,L.C.; Nascimento,M.C.; Pannuti,C.S.. |
Human herpesvirus 8 (HHV-8) is a newly described herpesvirus that is etiologically associated with all forms of Kaposi's sarcoma (KS). Seroepidemiological studies have shown high prevalence rates of HHV-8 antibodies among men who have sex with men (MSM) and AIDS patients, African children, Brazilian Amerindians, and elderly individuals in certain regions of Europe. The aim of the present study was to determine the prevalence of HHV-8 antibodies in healthy children and young adults from different cities in São Paulo State, and in a population at high risk for HHV-8 infection: HIV-negative MSM, and AIDS patients with and without KS. Antibodies to HHV-8 latency-associated nuclear antigen and lytic-phase antigens were detected by immunofluorescence assays. In... |
Tipo: Info:eu-repo/semantics/other |
Palavras-chave: HHV-8; Seroprevalence; AIDS; Kaposi's sarcoma; Immunofluorescence assay; Latency-associated nuclear antigen; Lytic-phase antigens. |
Ano: 2004 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2004000100017 |
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