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Seroprevalence of human herpesvirus 8 infection in children born to HIV-1- infected women in São Paulo, Brazil BJMBR
Machado,D.M.; Sumita,L.M.; Pannuti,C.S.; Succi,R.C.M.; Moraes-Pinto,M.I.; Souza,V.A.U.F..
Human herpesvirus-8 (HHV-8) appears to be transmitted mainly by sexual contact. However, several studies suggest that in developing countries the infection may be acquired early in life by routes other than sexual transmission. The present study estimated the seroprevalence of HHV-8 in Brazilian children born to HIV-1-infected mothers. The serum samples were collected in a cross-sectional cohort study from 99 children born to HIV-infected mothers (median age 3.27 years; range 1.5-13.8 years) attending the outpatient clinic of the Federal University of São Paulo. IgG antibodies to HHV-8 latency-associated nuclear antigen and lytic phase antigens were detected by immunofluorescence assays. The samples tested were collected from children aged 12 months or...
Tipo: Info:eu-repo/semantics/other Palavras-chave: HHV-8; Seroprevalence; AIDS; Children; LANA-IFA; Lytic-IFA.
Ano: 2005 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2005000200012
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Prevalence of antibodies to human herpesvirus-8 in populations with and without risk for infection in São Paulo State BJMBR
Souza,V.A.U.F.; Sumita,L.M.; Freire,W.; Sato,H.K.; Grandi,J.L.; Pierrotti,L.C.; Nascimento,M.C.; Pannuti,C.S..
Human herpesvirus 8 (HHV-8) is a newly described herpesvirus that is etiologically associated with all forms of Kaposi's sarcoma (KS). Seroepidemiological studies have shown high prevalence rates of HHV-8 antibodies among men who have sex with men (MSM) and AIDS patients, African children, Brazilian Amerindians, and elderly individuals in certain regions of Europe. The aim of the present study was to determine the prevalence of HHV-8 antibodies in healthy children and young adults from different cities in São Paulo State, and in a population at high risk for HHV-8 infection: HIV-negative MSM, and AIDS patients with and without KS. Antibodies to HHV-8 latency-associated nuclear antigen and lytic-phase antigens were detected by immunofluorescence assays. In...
Tipo: Info:eu-repo/semantics/other Palavras-chave: HHV-8; Seroprevalence; AIDS; Kaposi's sarcoma; Immunofluorescence assay; Latency-associated nuclear antigen; Lytic-phase antigens.
Ano: 2004 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2004000100017
Registros recuperados: 2
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