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| Pal,Savita; Mishra,Arvind; Rawat,Arun Kumar; Gautam,Sudeep; Maurya,Rakesh; Srivastava,Arvind K.. |
| The present study was undertaken to investigate the antidiabetic potential of tap roots of Potentilla fulgens in streptozotocin induced diabetic rat models. The crude powder, ethanolic, ethanolic: aqueous and aqueous extracts of tap roots were administered to normoglycemic- and streptozotocin (STZ)-induced diabetic rats in a single dose study. The ethanolic extract showed significant improvement in oral glucose tolerance and antihyperglycemic effect on sucrose loaded normal rats and STZ-induced diabetic rats. Of the isolated aqueous, n-butanol, chloroform and n-hexane soluble fractions of the active ethanolic extract of the roots, the aqueous fraction (100 mg/kg body weight) showed significant blood glucose lowering effect on STZ-induced diabetic rats. In... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Antidiabetic activity; Antihyperglycemic Activity; Antidyslipidemic activity; Potentilla fulgens roots; Alpha (α)-glucosidase enzyme. |
| Ano: 2016 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132016000100318 |
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