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	Provedor de dados BJID (2) Autor Stover,Kayla R. (2) Barber,Katie E. (1) Bell,Allison M. (1) Cleary,John D. (1) King,S. Travis (1) Otting,Kristin A. (1) Parham,Jason J. (1) Mais... Palavra-chave Antimicrobial stewardship program (1) Beta-lactams (1) Drug interactiona (1) Galactomannan (1) Meropenem (1) Pharmaceutical (1) Piperacillin (1) Piperacillin–tazobactam (1) Mais... Tipo do documento Info:eu-repo/semantics/other (1) Info:eu-repo/semantics/report (1) Ano 2016 (1) 2014 (1) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Impact of piperacillin-tazobactam shortage on meropenem use: implications for antimicrobial stewardship programs BJID Barber,Katie E.; Bell,Allison M.; King,S. Travis; Parham,Jason J.; Stover,Kayla R.. ABSTRACT Drug shortages pose a clear detriment to antimicrobial stewardship (AS) efforts. Our objective was to evaluate the effect of a piperacillin-tazobactam shortage on meropenem use, related costs, and associated changes in AS activity. A quasi-experimental quality improvement review compared adult patients receiving meropenem ≥72 h three months pre-shortage and three months during the shortage. 320 patients were included (pre-shortage: 103; shortage: 217). Baseline characteristics were similar, but the length of stay was slightly longer in pre-shortage [19 (11-32) days] versus shortage [16 (11-32) days] (p = 0.094). In pre-shortage and shortage, median days of therapy and estimated meropenem cost were 7 (5-11) and 7 (5-10) and $309.93... Tipo: Info:eu-repo/semantics/other Palavras-chave: Piperacillin; Meropenem; Pharmaceutical; Antimicrobial stewardship program. Ano: 2016 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702016000600631 Drug–laboratory interaction between beta-lactam antibiotics and the galactomannan antigen test used to detect mould infections BJID Otting,Kristin A.; Stover,Kayla R.; Cleary,John D.. Several studies have demonstrated that piperacillin/tazobactam produces a false-positive result for the galactomannan antigen test. However, the most recent literature has demonstrated that this interaction is no longer a concern. There is little information regarding the drug–laboratory interaction with the generics of piperacillin/tazobactam or other broad-spectrum beta-lactams, such as ceftaroline, doripenem, imipenem/cilastatin, and meropenem. The purpose of this study was to determine if a drug–laboratory interaction exists with these antibiotics. Tests showed that one lot of imipenem/cilastatin by Hospira Healthcare India Private Limited produced a false-positive result for the galactomannan antigen test. All other medications tested, including... Tipo: Info:eu-repo/semantics/report Palavras-chave: Piperacillin–tazobactam; Galactomannan; Beta-lactams; Drug interactiona. Ano: 2014 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702014000500544 Registros recuperados: 2 Primeira ... 1 ... Última

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