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| Su,L; Wang,J; Huang,J; Zhao,Y; Jiang,H; Li,H. |
| ABSTRACT To investigate the hypothesis that APS can attenuate E. coli-induced microvascular dysfunction in chicken intestine, 60 0-day old male chickens were divided into three groups with 5 replications of 4 chicks. Chicken in the APS group were treated with 15 mg APS daily while the others were given 0 mg APS for 6 days. Then all 7-day old chicken were injected intraperitoneally by E. coli, except for the chicken in the control group. After 4 h, all chicken’s intestinal samples were collected to detect gene expressions involved in inflammatory factors and adhesion molecules. Results showed that APS attenuated the signs of edema and hemorrhage in 7-day old chicken intestinal mucosa which were induced by E. coli injection. Consistently, APS significantly... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Astragalus polysaccharide; Escherichia coli; Intercellular adhesion molecule -1; Nuclear factor - κB; Vascular cell adhesion molecule -1. |
| Ano: 2019 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-635X2019000300302 |
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