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Immunohistochemical and Histopathological Changes in the Skin of Rats after Administration of Lead Acetate International Journal of Morphology
Sula,Bilal; Deveci,Engin; Özevren,Hüseyin; Ekinci,Cenap; Elbey,Bilal.
Lead acetate is a chemical compound. Sources of human exposure to this metal include many foods, drinking water and dust. The aim of this study was to determine the immunohistochemical and histopathological changes on the face skin after lead acetate application. Wistar Albino rats (180-200 g body weight) were divided into a controlled and lead acetate-exposed group. Rats received lead acetate at 500 ppm in their drinking water for 60 days. Both groups were fed with the same standard food, but lead acetate was added to the drinking water. During the experimental period, blood samples were drawn from the abdominal aorta of the anesthetised animals. At the end of exposure, body weight and blood lead levels were measured. Sections of rat facial skin were...
Tipo: Journal article Palavras-chave: Lead acetate; Skin; Proliferating cell nuclear antigen; Vimentin.
Ano: 2016 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022016000300017
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