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	Provedor de dados BJPS (2) Autor Ali,Gowhar (2) Shah,Rehmat (2) Subhan,Fazal (2) Sultan,Syed Muhammad (2) Ahmad,Hussain (1) Haq,Matiul (1) Khan,Qasim Riaz (1) Ullah,Ihsan (1) Ullah,Sami (1) Mais... Palavra-chave Pancreas (2) Antipsychotics (1) D2 antagonist (1) Histopathology (1) Insulin (1) Olanzapine (1) Quetiapine (1) Risperidone (1) Risperidone/antipsychotics/oral administration/effects (1) Mais... Tipo do documento Info:eu-repo/semantics/article (2) Ano 2019 (1) 2018 (1) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Metabolic dysregulation in early onset psychiatric disorder before and after exposure to antipsychotic drugs BJPS Shah,Rehmat; Subhan,Fazal; Sultan,Syed Muhammad; Haq,Matiul; Ahmad,Hussain; Khan,Qasim Riaz; Ali,Gowhar; Ullah,Sami; Ullah,Ihsan. Antipsychotic Drugs (APDs) are being widely prescribed to treat various disorders, including schizophrenia and bipolar disorder; however, abnormal glucose metabolism and weight gain have been reported with Atypical Anti-Psychotic drugs (AAPDs) that can lead to insulin-resistance and type 2 diabetes mellitus. The study was designed to assess various biochemical parameters including insulin and blood sugar before and after exposure to APDs in order to exclude the involvement of psychiatric disorders and certain other factors in metabolic dysregulations. Fifty seven APDs-naïve patients with first episode psychosis were divided into six groups who received olanzapine, quetiapine, risperidone, aripiprazole, haloperidol or combination of olanzapine with... Tipo: Info:eu-repo/semantics/article Palavras-chave: Olanzapine; Quetiapine; Risperidone; Antipsychotics; Pancreas; Insulin. Ano: 2019 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502019000100535 Short-term oral administration of risperidone induces pancreatic damage and hyperamylasemia in Sprague-dawley rats BJPS Shah,Rehmat; Subhan,Fazal; Sultan,Syed Muhammad; Ali,Gowhar. Risperidone is an atypical antipsychotic acting mainly as a dopamine D2 and serotonin 5-HT2 receptors antagonist prescribed in the treatment of schizophrenia and various affective disorders. Risperidone has been reported to be associated with weight gain, panreatitis and type 2 diabetes mellitus. Various mechanisms of risperidone-induced toxicities have been reported but the histology of tissues especially pancreas has never been studied. Therefore, the current study was designed to elucidate the toxic effects of chronic administration of risperidone on pancreas, liver and kidneys. Animals (rats) of either gender were divided into two groups, the risperidone and control groups. Risperidone was administered in a dose of 2.5 mg/kg/d for three weeks. The... Tipo: Info:eu-repo/semantics/article Palavras-chave: Risperidone/antipsychotics/oral administration/effects; Histopathology; D2 antagonist; Pancreas. Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502018000400629 Registros recuperados: 2 Primeira ... 1 ... Última

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