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	Provedor de dados Genet. Mol. Biol. (1) Autor Dong,Xue-Song (1) Song,Chun-Qing (1) Sun,Da-Zhuang (1) Xu,Yong-Min (1) Palavra-chave A549 cells (1) Apoptosis (1) MAPKs (1) Mitochondria (1) Paraquat (1) Tipo do documento Info:eu-repo/semantics/article (1) Ano 2020 (1) País Brazil (1) Idioma Inglês (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 1 Primeira ... 1 ... Última Role of the MAPK pathway in human lung epithelial-like A549 cells apoptosis induced by paraquat Genet. Mol. Biol. Sun,Da-Zhuang; Song,Chun-Qing; Xu,Yong-Min; Dong,Xue-Song. Abstract This study aims to investigate the value of mitogen-activated protein kinases (MAPKs) for paraquat (PQ)-induced apoptosis in human lung epithelial-like A549 cells and the specific mechanism. A549 cell apoptosis were induced by PQ. These cells were divided into six groups: control group (cells were cultured in RPMI-1640 medium); SP600125 group (cells were preconditioned with SP600125); SB203580 group (cells were preconditioned with SB203580); PQ group (cells were treated with PQ); SP600125+PQ group (cells were preconditioned with SP600125 following PQ); SB203580+PQ group (cells were preconditioned with SB203580 following PQ). The cell survival rate, apoptosis rate, and activities of caspase-3 and -9 were detected. When compared with the control... Tipo: Info:eu-repo/semantics/article Palavras-chave: Paraquat; A549 cells; MAPKs; Mitochondria; Apoptosis. Ano: 2020 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572020000400701 Registros recuperados: 1 Primeira ... 1 ... Última

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