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The effect of physical exercise and caloric restriction on the components of metabolic syndrome BJPS
Torres-Leal,Francisco Leonardo; Capitani,Mariana Dutilh de; Tirapegui,Julio.
Recent studies of the effects of physical exercise and caloric restriction have found several benefits on the metabolic and cardiovascular risk factors related to metabolic syndrome (MS). This review examines the current state of knowledge of the effects of physical exercise on the main pathologies associated with MS: obesity, insulin resistance, type 2 diabetes mellitus (DM2), dyslipidemias and hypertension. Although there are only a few randomized and controlled studies that evaluated the prevention and treatment of MS, strong evidence from controlled studies indicates that lifestyle changes that include regular physical exercise and caloric restriction are effective in preventing and treating DM2 in overweight individuals with reduced glucose tolerance....
Tipo: Info:eu-repo/semantics/article Palavras-chave: Physical activity; Metabolic syndrome; Insulin/resistance; Type 2 diabetes mellitus; Obesity; Nutrition.
Ano: 2009 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502009000300003
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Effects of administering testosterone undecanoate in rats subjected to physical exercise: effects on the estrous cycle, motor behavior and morphology of the liver and kidney BJPS
Bento-Silva,Moisés Tolentino; Martins,Maria do Carmo de Carvalho e; Torres-Leal,Francisco Leonardo; Barros,Talvany Luiz; Carvalho,Ingrid Lara do Nascimento Ferreira de; Carvalho Filho,Hugo Aparecido; Almeida,Fernanda Regina de Castro.
The aim of the work was evaluate the effects of testosterone undecanoate (TU) treatment combined with moderate physical training on: the estrous cycle, body weight (BW), motor behavior (MB), and the morphohistology of the reproductive system, the liver and kidney in rats. Female Wistar rats (180 g - 250 g) were divided as follows: sedentary + TU (S + TU), trained + TU (T + TU), sedentary + vehicle (S + V), trained + vehicle (T + V). The rats swam 50 min/Day, strapped with a 5% BW load, for 4 weeks. During this training, (BW) was monitored daily as well as the estrous cycle (EC) by vaginal smear. The TU (15 mg/kg s.c) was administered 3 times/week for 4 weeks. At the end of the study, data on MB, BW and morphohistopathological changes in viscera were...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Androgenic anabolic steroids/experimental study; Endurance training; Testosterone undecanoate.
Ano: 2010 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502010000100009
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Protein synthesis regulation by leucine BJPS
Vianna,Daiana; Teodoro,Gabriela Fullin Resende; Torres-Leal,Francisco Leonardo; Tirapegui,Julio.
In vivo and in vitro studies have demonstrated that high protein diets affect both protein synthesis and regulation of several cellular processes. The role of amino acids as substrate for protein synthesis has been established in the literature. However, the mechanism by which these amino acids modulate transcription and regulate the mRNA translation via mTOR-dependent signaling pathway has yet to be fully determined. It has been verified that mTOR is a protein responsible for activating a cascade of biochemical intracellular events which result in the activation of the protein translation process. Of the aminoacids, leucine is the most effective in stimulating protein synthesis and reducing proteolysis. Therefore, it promotes a positive nitrogen balance,...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Leucine; Protein synthesis; Transcription Factors; MTOR; Translation Protein.
Ano: 2010 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502010000100004
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Obesity, inflammation, and insulin resistance BJPS
Martins,Luana Mota; Oliveira,Ana Raquel Soares; Cruz,Kyria Jayanne Clímaco; Torres-Leal,Francisco Leonardo; Marreiro,Dilina do Nascimento.
White adipose tissue (WAT) is considered an endocrine organ. When present in excess, WAT can influence metabolism via biologically active molecules. Following unregulated production of such molecules, adipose tissue dysfunction results, contributing to complications associated with obesity. Previous studies have implicated pro- and anti-inflammatory substances in the regulation of inflammatory response and in the development of insulin resistance. In obese individuals, pro-inflammatory molecules produced by adipose tissue contribute to the development of insulin resistance and increased risk of cardiovascular disease. On the other hand, the molecules with anti-inflammatory action, that have been associated with the improvement of insulin sensitivity, have...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Obesity; Inflammation; Adipose tissue; Adipokines; Insulin resistance.
Ano: 2014 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502014000400677
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