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| Santana,Nelma Pereira de; Freitas,Luiz A.R. de; Lyra,André Castro; Paraná,Raymundo; Santana,Genoile; Trepo,Christian; Lyra,Luiz G.C.. |
| Patients with chronic hepatitis C can have variable clinical progression. Hepatic histological alterations appear to be milder in asymptomatic subjects who have persistently normal ALT levels. AIMS: To evaluate the severity of histological liver alterations in blood donors with normal and elevated ALT levels. METHODS: We evaluated volunteer blood donors from the main blood bank of the city of Salvador-Brazil. Those who were anti-HCV positive were invited to participate in the study. Serum ALT and AST levels were measured at two time points, two months apart. Donors were divided into two groups: group I, individuals with ALT > 1.5 times the upper limit of normal in at least one time point and group II, individuals with normal or near normal ALT, at both... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: ALT levels; Liver alterations; HCV; Northeast-Brazil. |
| Ano: 2005 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702005000200003 |
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| Almeida,Delvone; Tavares-Neto,José; Trepo,Christian; Almeida,Alessandro; Mello,Caroline; Chemin,Isabelle; Paraná,Raymundo. |
| A sentinel study on viral hepatitis is currently being carried out in the village of Cavunge in a semiarid rural region of the state of Bahia, northeastern Brazil. This study has identified individuals in whom anti-HBc IgG was the only serological marker for hepatitis B virus (HBV). This serological pattern may constitute evidence of occult HBV infection. This study Investigated the possibility of occult hepatitis B virus infection in individuals in a rural community who tested positive for anti-HBc IgG alone. A cross-sectional population-based study. ELISA III was performed on serum samples to test for serological viral markers, and ultrasensitive PCR (US-PCR) was used to assess viremia. Among the 1,536 serum samples, 3.6% (n=55) were positive for... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Anti-HBc alone; Hepatitis B virus; Occult hepatitis B; Ultrasensitive PCR. |
| Ano: 2008 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702008000400010 |
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