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	Provedor de dados BJMBR (1) Autor MacIntosh,B.R. (1) Rassier,D.E. (1) Tubman,L.A. (1) Palavra-chave Atrophy (1) Ca2+ availability (1) Myosin light chains (1) Potentiation (1) Tetrodotoxin (TTX) (1) Tipo do documento Info:eu-repo/semantics/article (1) Ano 1999 (1) País Brazil (1) Idioma Inglês (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 1 Primeira ... 1 ... Última Staircase in mammalian muscle without light chain phosphorylation BJMBR Rassier,D.E.; Tubman,L.A.; MacIntosh,B.R.. In disuse atrophied skeletal muscle, the staircase response is virtually absent and light chain phosphorylation does not occur. The purpose of the present study was to determine if staircase could be restored in atrophied muscle with continued absence of myosin light chain phosphorylation, by reducing what appears to be an otherwise enhanced calcium release. Control (untreated) and sham-operated female Sprague-Dawley rats were compared with animals after 2 weeks of complete inactivity induced by tetrodotoxin (TTX) application to the left sciatic nerve. In situ isometric contractile responses of rat gastrocnemius muscle were analyzed before and after administration of dantrolene sodium (DS), a drug which is known to inhibit Ca2+ release in skeletal muscle.... Tipo: Info:eu-repo/semantics/article Palavras-chave: Potentiation; Ca2+ availability; Tetrodotoxin (TTX); Atrophy; Myosin light chains. Ano: 1999 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1999000100018 Registros recuperados: 1 Primeira ... 1 ... Última

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