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| Watanabe, Ken-ichi; Chambers, James K.; Uchida, Kazuyuki; Nibe, Kazumi; Ushio, Nanako; Horiuchi, Noriyuki; Kobayashi, Yoshiyasu; Nakayama, Hiroyuki. |
| The atypical cutaneous tumor of a 9-year-old mixed breed female dog was examined. The tumor was well-demarcated and histologically composed of a trichoblastic area, tricholemmal area and apocrine glandular area. Neoplastic cells in trichoblastic area and tricholemmal area had PAS-positive granules in the cytoplasm and were positive for pan-cytokeratin, cytokeratin 5/6, 14 and 19 and p63. Neoplastic cells in trichoblastic area were also positive for cytokeratin 15 and CD34. Neoplastic cells in apocrine glandular area were positive for pan-cytokeratin and cytokeratin 7,18 and 19. Myoepithelial cell proliferation with osteocartilaginous metaplasia was observed in this area. Since neoplastic cells showed multiphenotypic differentiation for hair follicles and... |
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Palavras-chave: Cutaneous mixed tumor; Dog; Hair follicle; Multiphenotypic differentiation. |
| Ano: 2017 |
URL: http://ir.obihiro.ac.jp/dspace/handle/10322/4453 |
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