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| PASSARELLI-ARAUJO,HEMANOEL; PALMEIRO,JUSSARA K.; MOHARANA,KANHU C.; PEDROSA-SILVA,FRANCISNEI; DALLA-COSTA,LIBERA M.; VENANCIO,THIAGO M.. |
| Abstract Aminoglycosides are a class of antibiotics that play a key role in antimicrobial treatment of Multidrug resistant (MDR) Gram-negative bacilli, typically in combination with β-lactams. Ribosomal 16S RNA modification by methyltransferases (e.g. RmtG) is an aminoglycoside resistance mechanism that, along with the occurrence carbapenem-resistant Enterobacteriaceae (CRE), has become a clinical concern. In Brazil, rmtG genes were initially reported in Klebsiella pneumoniae, and monitoring isolates from other species carrying this gene is critical for epidemiological studies and to prevent dissemination. Here we report the presence of rmtG in Klebisella aerogenes D3 and characterize its genetic context in comparison to isolates from other species.... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Klebsiella aerogenes; Aminoglycoside; 16S rRNA methyltransferases; Multidrug resistance. |
| Ano: 2019 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652019000200602 |
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