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	Provedor de dados BJPS (2) Autor Bentley,Maria Vitória Lopes Badra (2) Vicentini,Fabiana Testa Moura de Carvalho (2) Borgheti-Cardoso,Lívia Neves (1) Fonseca,Maria José Vieira (1) Georgetti,Sandra Regina (1) Gratieri,Tais (1) Mais... Palavra-chave DPPH• (1) High performance liquid chromatography (1) Liquid crystalline systems/development (1) Nicotine/controlled transdermal delivery (1) Nicotine/transdermal patches (1) Quercetin/extraction (1) Quercetin/liberation (1) Quercetin/quantification (1) Skin irritation/control/in vitro study (1) Skin irritation/use of transdermal patches. (1) Skin penetration in vitro/study (1) Topical formulations/analysis (1) Vitamin E TPGS (1) Mais... Tipo do documento Info:eu-repo/semantics/article (2) Ano 2016 (1) 2009 (1) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Assessment of in vitro methodologies to determine topical and transdermal delivery of the flavonoid quercetin BJPS Vicentini,Fabiana Testa Moura de Carvalho; Georgetti,Sandra Regina; Bentley,Maria Vitória Lopes Badra; Fonseca,Maria José Vieira. To be effective against the oxidative damages induced by UVB irradiation in the skin, the drug needs to release from the formulation in which it was incorporated and reach the skin layers where the ROS are generated. Thus, it is very important the development of a robust and sensitive methodology to extract and quantify in different skin layers the antioxidant agent delivered from topical formulations. Therefore, in the present work suitable methods to extract and quantify quercetin in skin samples and receptor phase after in vitro penetration studies were developed. The results demonstrated that the recovery from two different layers of skin, the SC and [E+D], using two different methods of quantification (DPPH• assay and HPLC, respectively), was 93.8 %... Tipo: Info:eu-repo/semantics/article Palavras-chave: Topical formulations/analysis; Quercetin/quantification; Quercetin/extraction; Quercetin/liberation; Skin penetration in vitro/study; High performance liquid chromatography; DPPH•. Ano: 2009 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502009000200022 Liquid crystalline systems containing Vitamin E TPGS for the controlled transdermal nicotine delivery BJPS Borgheti-Cardoso,Lívia Neves; Vicentini,Fabiana Testa Moura de Carvalho; Gratieri,Tais; Bentley,Maria Vitória Lopes Badra. ABSTRACT Transdermal nicotine patches have been used in smoking cessation therapy, suggested for the treatment of skin disorders with eosinophilic infiltration and have been found to improve attention performance in patients with Alzheimer's disease and age-associated memory impairment. However, skin irritation with extended patch use is still a problem. The aim of this work was to develop a simple to prepare liquid crystalline system containing vitamin E TPGS that would be able to control nicotine delivery and reduce irritation and sensitization problems. The liquid crystalline phases were macroscopically characterized by visual analysis and examined microscopically under a polarized light microscope. Topical and transdermal delivery of nicotine were... Tipo: Info:eu-repo/semantics/article Palavras-chave: Nicotine/transdermal patches; Nicotine/controlled transdermal delivery; Liquid crystalline systems/development; Vitamin E TPGS; Skin irritation/control/in vitro study; Skin irritation/use of transdermal patches.. Ano: 2016 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502016000100021 Registros recuperados: 2 Primeira ... 1 ... Última

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