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	Provedor de dados Nature Precedings (3) Autor Vikas Jain (3) Ranjit Singh (2) Girish Kumar Gupta (1) Prabhat Ranjan Mishra (1) Palavra-chave Pharmacology (3) Chemistry (2) Tipo do documento Manuscript (2) Poster (1) Ano 2009 (3) País United Kingdom (3)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 3 Primeira ... 1 ... Última Paclitaxel delivery by micro/nano encapsulation using layer-by-layer assembly Nature Precedings Girish Kumar Gupta; Vikas Jain; Prabhat Ranjan Mishra. A novel formulation of paclitaxel (PTX) has been developed by providing multilayer assembly over drug loaded porous CaCO3 microparticles (CaCO3 MP) using combination of biocompatible and biodegradable polyelectrolytes (PE’s). PTX was encapsulated into the nanopores of preformed CaCO3 MP prepared by the co-precipitation method. Infrared (IR) and X-ray diffraction (XRD) provides evidences that PTX has been encapsulated into nanopores of CaCO3 MP and not crystallized on the surface. PTX loaded CaCO3 MP (CaCO3-PTX) was found to be highly stabilized against thermal decomposition as evinced by thermo gravimetric analysis (TGA) indicating decomposition at 600°C and 250°C for CaCO3-PTX and PTX respectively. The multilayer assembly over... Tipo: Poster Palavras-chave: Pharmacology. Ano: 2009 URL: http://precedings.nature.com/documents/2812/version/1 Development and Characterization of Eudragit RS 100 Loaded Microsponges and its Colonic Delivery Using Natural Polysaccharides Nature Precedings Vikas Jain; Ranjit Singh. In the present work, paracetamol loaded eudragit based microsponges were prepared using quasi-emulsion solvent diffusion method. The compatibility of the drug with various formulation components was established. Process parameters were analyzed in order to optimize the formulation. Shape and surface morphology of the microsponges were examined using scanning electron microscopy. The colon specific formulations were prepared by compression coating of microsponges with pectin:hydroxypropylmethylcellulose (HPMC) mixture followed by tabletting. The in vitro dissolution studies were done on all formulations and the results were evaluated kinetically and statically. The kinetics of release study showed that the release data followed Higuchi matrix and the main... Tipo: Manuscript Palavras-chave: Chemistry; Pharmacology. Ano: 2009 URL: http://precedings.nature.com/documents/3676/version/2 Development and Characterization of Eudragit RS 100 Loaded Microsponges and its Colonic Delivery Using Natural Polysaccharides Nature Precedings Vikas Jain; Ranjit Singh. In the present work, paracetamol loaded eudragit based microsponges were prepared using quasi-emulsion solvent diffusion method. The compatibility of the drug with various formulation components was established. Process parameters were analyzed in order to optimize the formulation. Shape and surface morphology of the microsponges were examined using scanning electron microscopy. The colon specific formulations were prepared by compression coating of microsponges with pectin:hydroxypropylmethylcellulose (HPMC) mixture followed by tabletting. The in vitro dissolution studies were done on all formulations and the results were evaluated kinetically and statically. The kinetics of release study showed that the release data followed Higuchi matrix and the main... Tipo: Manuscript Palavras-chave: Chemistry; Pharmacology. Ano: 2009 URL: http://precedings.nature.com/documents/3676/version/1 Registros recuperados: 3 Primeira ... 1 ... Última

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