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Usefulness of pharmacy dispensing records in the evaluation of adherence to antiretroviral therapy in Brazilian children and adolescents BJID
Ernesto,Aline Santarem; Lemos,Renata Muller Banzato Pinto de; Huehara,Maria Ivone; Morcillo,André Moreno; Vilela,Maria Marluce dos Santos; Silva,Marcos Tadeu Nolasco da.
INTRODUCTION: Adherence, which is crucial to the success of antiretroviral therapy (HAART), is currently a major challenge in the care of children and adolescents living with HIV/AIDS. OBJECTIVE: To evaluate the prevalence of nonadherence to HAART using complementary instruments in a cohort of children and adolescents with HIV/AIDS followed in a reference service in Campinas, Brazil. METHODS: The level of adherence of 108 patients and caregivers was evaluated by an adapted standardized questionnaire and pharmacy dispensing records (PDR). Non-adherence was defined as a drug intake lower than 95% (on 24-hour or seven-day questionnaires), or as an interval of 38 days or more for pharmacy refills. The association between adherence and clinical, immunological,...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Acquired immunodeficiency; Syndrome; Child; Adolescent; Highly active antiretroviral therapy; Medication adherence.
Ano: 2012 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702012000400001
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Endocarditis by Kocuria rosea in an immunocompetent child BJID
Moreira,Jorge Salomão; Riccetto,Adriana Gut Lopes; Silva,Marcos Tadeu Nolasco da; Vilela,Maria Marluce dos Santos.
Kocuria roseabelongs to genus Kocuria(Micrococcaceaefamily, suborder Micrococcineae, order Actinomycetales) that includes about 11 species of bacteria. Usually, Kocuria spare commensal organisms that colonize oropharynx, skin and mucous membrane; Kocuria spinfections have been described in the last decade commonly affecting immunocompromised patients, using intravenous catheter or peritoneal dialysis. These patients had mainly bacteremia/recurrent sepsis. We hereby describe the case of a 10-year-old girl, immunocompetent, who had endocarditis/sepsis by K. roseawhich was identified in five different blood cultures by Vitek2 ID-GPC card (BioMérieux, France). Negative HIV serology, blood count within normal range of leukocytes/neutrophils and lymphocytes,...
Tipo: Info:eu-repo/semantics/other Palavras-chave: Infectious endocarditis; Kocuria roseaImmune system Children.
Ano: 2015 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702015000100082
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Partial chemical and functional characterization of milk whey products obtained by different processes Ciênc. Tecnol. Aliment.
Ziegler,Fabiane La Flor; Castro,Georgia Alvares; Moreno,Yara Maria Franco; Oya,Vanessa; Vilela,Maria Marluce dos Santos; Sgarbieri,Valdemiro Carlos.
Whey protein samples (S-1 to S-5) were tested in vivo and in vitro for nutritional properties and selected bioactivities. Weanling male Wistar rats fed modified AIN-93G (12 g protein.100 g-1) diets for 21 days were used the in vivo studies. The nutritional parameters did not differ among the protein diets tested. Erythrocyte glutathione content was considered high and was higher for S-3, but liver glutathione was the same for all dietary groups. For S-3, cytokine secretion (IL-10 and TNF-α) by human peripheral blood mononuclear cells (in RPMI-1640 medium) was higher in the absence of antigen than in the presence of BCG antigen. Interleukin-4 secretion was repressed in all treatments. The IC50, whey protein concentration required to inhibit 50% of the...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Whey proteins; Nutritive value; Immune modulation; Glutathione; Cytokines.
Ano: 2012 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0101-20612012000100009
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