|
|
|
|
|
| Shingfield, Kevin J.; Viitala, Sirja; Leskinen, Heidi; Vilkki, Johanna. |
| Nutritional regulation of milk and meat fatty acid composition has been the subject of intense research during the last few decades. Considerable progress has been made towards understanding the role of diet on enhancing the nutritional value of ruminantderived foods while more recent studies have attempted to elucidate the molecular mechanisms underlying the changes in milk and tissue lipid fatty acid composition in ruminants. Diet is the major environmental factor influencing the CLA content of ruminant milk whilst the effects of genotype, stage of lactation and parity are relatively minor (Palmquist el al. 2005). Concentrations of CLA in ruminant meat are dependent on diet, gender, slaughter weight and breed with evidence of variable enrichment... |
| Tipo: Conference paper, poster, etc. |
Palavras-chave: Food security; Food quality and human health. |
| Ano: 2010 |
URL: http://orgprints.org/18290/1/Shingfield.doc |
| |
|
| |
|
|
| Bouwman, Aniek C.; Daetwyler, Hans D.; Chamberlain, Amanda J.; Hurtado Ponce, Carla; Sargolzaei, Mehdi; Schenkel, Flavio S.; Sahana, Goutam; Govignon-Gion, Armelle; Boitard, Simon; Dolezal, Marlies; Pausch, Hubert; Brøndum, Rasmus F.; Bowman, Phil J.; Thomsen, Bo; Guldbrandtsen, Bernt; Lund, Morgns S.; Servin, Bertrand; Garrick, Dorian J.; Reecy, James; Vilkki, Johanna; Bagnato, Alessandro; Wang, Min; Hoff, Jesse L.; Schnabel, Robert D.; Taylor, Jeremy F.; Vinkhuyzen, Anna A. E.; Panitz, Frank; Bendixen, Christian; Holm, Lars-Erik; Gredler, Birgit; Hozé, Chris; Boussaha, Mekki; Sanchez, Marie-Pierre; Rocha, Dominique; Capitan, Aurelien; Tribout, Thierry; Barbat, Anne; Croiseau, Pascal; Drögemüller, Cord; Jagannathan, Vidhya; Vander Jagt, Christy; Bieber, Anna; Purfield, Deidre C.; Berry, Donagh P.; Emmerling, Reiner; Götz, Kay-Uwe; Frischknecht, Mirjam; Russ, Ingolf; Sölkner, Johann; Van Tassel, Curtis P.; Fries, Ruedi; Stothard, Paul; Veerkamp, Roel F.; Boichard, Didier; Goddard, Mike E.; Hayes, Ben J.. |
| Stature is affected by many polymorphisms of small effect in humans1. In contrast, variation in dogs, even within breeds, has been suggested to be largely due to variants in a small number of genes2,3. Here we use data from cattle to compare the genetic architecture of stature to those in humans and dogs. We conducted a meta-analysis for stature using 58,265 cattle from 17 populations with 25.4 million imputed whole-genome sequence variants. Results showed that the genetic architecture of stature in cattle is similar to that in humans, as the lead variants in 163 significantly associated genomic regions (P < 5 × 10−8) explained at most 13.8% of the phenotypic variance. Most of these variants were noncoding, including variants that were also expression... |
| Tipo: Journal paper |
Palavras-chave: Dairy cattle; Beef cattle; Breeding and genetics. |
| Ano: 2018 |
URL: http://orgprints.org/35102/1/Bouwman-etal-2018-NatureGenetics-Vol50-p362-367.pdf |
| |
|
|
|
