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Preparation and evaluation of a biomimetic scaffold with porosity gradients in vitro Anais da ABC (AABC)
Wang,Qianbin; Wang,Qiguang; Wan,Changxiu.
A novel biodegradable scaffold based on mimetic a natural bone tissue morphology with a porosity gradient structure was prepared in this paper. The result of surface morphology indicated that a graded porous structure was formed in the fabricated scaffold, where the dense layer (0%) was connected with the most porous layer (60%) by a middling porous layer (30%). To evaluate the degradability, graded porous scaffolds compared with homogeneous scaffolds were placed into a Tris-HCl buffer solution (pH = 7.4) for 28 days. It was found that both scaffolds presented the same degradation trend, and the graded porous structure did not change the original degradability of the scaffold. Moreover, the compressive strength of the graded porous scaffold was better than...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Biodegradable; Biomimetic; Graded porous scaffold; Compressive strength.
Ano: 2012 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652012000100003
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