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| Wangai, L.N; Kimani, F.T; Omar, S.A; Karanja, S.M; Nderu, D.W; Magoma, G; Mutua, D. |
| Development and spread of chloroquine (CQ) resistance led to its withdrawal in most malaria endemic countries. In Kenya, this occurred in 1998 when clinical efficacy dropped below 50%. Less than a decade after CQ was removed from routine use in Malawi, the drug has reversed to activity and is again effective for first-line treatment of uncomplicated malaria. There is a probability of a similar reversed activity in Kenya for more 10 years of its absence in uncomplicated Plasmodium falciparum malaria treatment. The present study was aimed at establishing the CQ resistance status in the country, 10 years after its withdrawal, by looking at high malaria transmission zone, Mbita, a malaria endemic area and some malaria epidemic areas of the Kenyan highlands.... |
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Palavras-chave: Plasmodium falciparum; Chloroquine (CQ); Resistance; Endemic; Epidemic. |
| Ano: 2011 |
URL: http://ir.obihiro.ac.jp/dspace/handle/10322/3096 |
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