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	Provedor de dados BJMBR (1) Genet. Mol. Biol. (1) Autor Wu,Kai (2) Hou,Yanhong (1) Li,Dan (1) Ouyang,Zhongming (1) Peng,Zhengsong (1) Wei,Shuhong (1) Yang,Zaijun (1) Zhang,Lin (1) Zhou,Yonghong (1) Mais... Palavra-chave Chronic atrophic gastritis (1) Copy number variation (1) Differentially expressed proteins (1) Genetic diversity (1) Molecular evolution (1) Proteasome activator subunit 1 (PSME1) (1) Proteomic study (1) Ribosomal protein S12 (RPS12) (1) Triticum (1) WAG-2 (1) Mais... Tipo do documento Info:eu-repo/semantics/article (2) Ano 2012 (1) 2011 (1) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Comparative proteomics analysis of chronic atrophic gastritis: changes of protein expression in chronic atrophic gastritis without Helicobacter pylori infection BJMBR Zhang,Lin; Hou,Yanhong; Wu,Kai; Li,Dan. Chronic atrophic gastritis (CAG) is a very common gastritis and one of the major precursor lesions of gastric cancer, one of the most common cancers worldwide. The molecular mechanism underlying CAG is unclear, but its elucidation is essential for the prevention and early detection of gastric cancer and appropriate intervention. A combination of two-dimensional gel electrophoresis and mass spectrometry was used in the present study to analyze the differentially expressed proteins. Samples from 21 patients (9 females and 12 males; mean age: 61.8 years) were used. We identified 18 differentially expressed proteins in CAG compared with matched normal mucosa. Eight proteins were up-regulated and 10 down-regulated in CAG when compared with the same amounts of... Tipo: Info:eu-repo/semantics/article Palavras-chave: Differentially expressed proteins; Chronic atrophic gastritis; Proteomic study; Ribosomal protein S12 (RPS12); Proteasome activator subunit 1 (PSME1). Ano: 2012 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2012000300014 Nucleotide diversity and molecular evolution of the WAG-2 gene in common wheat (Triticum aestivum L) and its relatives Genet. Mol. Biol. Wei,Shuhong; Peng,Zhengsong; Zhou,Yonghong; Yang,Zaijun; Wu,Kai; Ouyang,Zhongming. In this work, we examined the genetic diversity and evolution of the WAG-2 gene based on new WAG-2 alleles isolated from wheat and its relatives. Only single nucleotide polymorphisms (SNP) and no insertions and deletions (indels) were found in exon sequences of WAG-2 from different species. More SNPs and indels occurred in introns than in exons. For exons, exons+introns and introns, the nucleotide polymorphism Π decreased from diploid and tetraploid genotypes to hexaploid genotypes. This finding indicated that the diversity of WAG-2 in diploids was greater than in hexaploids because of the strong selection pressure on the latter. All dn/ds ratios were < 1.0, indicating that WAG-2 belongs to a conserved gene affected by negative selection. Thirty-nine of... Tipo: Info:eu-repo/semantics/article Palavras-chave: Copy number variation; Genetic diversity; Molecular evolution; Triticum; WAG-2. Ano: 2011 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572011000400013 Registros recuperados: 2 Primeira ... 1 ... Última

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