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Analysis of serum microRNA expression in male workers with occupational noise-induced hearing loss BJMBR
Li,Y.H.; Yang,Y.; Yan,Y.T.; Xu,L.W.; Ma,H.Y.; Shao,Y.X.; Cao,C.J.; Wu,X.; Qi,M.J.; Wu,Y.Y.; Chen,R.; Hong,Y.; Tan,X.H.; Yang,L..
Occupational noise-induced hearing loss (ONIHL) is a prevalent occupational disorder that impairs auditory function in workers exposed to prolonged noise. However, serum microRNA expression in ONIHL subjects has not yet been studied. We aimed to compare the serum microRNA expression profiles in male workers of ONIHL subjects and controls. MicroRNA microarray analysis revealed that four serum microRNAs were differentially expressed between controls (n=3) and ONIHL subjects (n=3). Among these microRNAs, three were upregulated (hsa-miR-3162-5p, hsa-miR-4484, hsa-miR-1229-5p) and one was downregulated (hsa-miR-4652-3p) in the ONIHL group (fold change >1.5 and Pbon value <0.05). Real time quantitative PCR was conducted for validation of the microRNA...
Tipo: Info:eu-repo/semantics/article Palavras-chave: MicroRNA; Noise-induced hearing loss; Serum; MiR-1229-5p; MAPK1.
Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2018000300601
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Prevalence of genital human papillomavirus among rural and urban populations in southern Yunnan province, China BJMBR
Baloch,Z.; Yuan,T.; Yindi,S.; Feng,Y.; Tai,W.; Liu,Y.; Liu,L.; Zhang,A.; Wang,B.; Wu,X.; Xia,X..
This study was designed to investigate and compare the HPV prevalence, genotypes distribution and associated risk factors in rural and urban women living in Xishuang Banna district, in the province of Yunnan. A total of 177 and 190 women from rural and urban areas were engaged, respectively. HPV DNA was amplified using the L1 consensus primers system (MY09/11 and GP5/6) and HPV GenoArray test was conducted for genotyping. Proportions were compared by chi-square test, and logistic regression was used to evaluate risk factors. A total of 54 women were positive for HPV DNA. Among rural women, 23 women were positive for HPV infection, of which 21 showed a single infection and 2 had a multiple infection. HPV-16 (10/23) was the most prevalent genotype followed...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Xishuang Banna; Prevalence; Genotype; Oncogenic; Rural; Urban.
Ano: 2016 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2016000600708
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Is endobronchial ultrasound-guided transbronchial needle aspiration with a stylet necessary for lymph node screening in lung cancer patients? BJMBR
Xu,Y.; Lin,J.; Jin,Y.; Wu,X.; Zheng,H.; Feng,J..
During endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA), a needle is commonly used with a stylet, although recently the stylet has been omitted. This prospective study aimed to compare the quality of specimens obtained by EBUS-TBNA performed with and without a stylet. Between November 2013 and November 2014, 131 patients with lung cancer underwent EBUS-TBNA, with a total of 148 mediastinal or hilar lymph nodes sampled both with and without an inner-stylet, yielding 296 cytological specimens. Specimens were scored cytologically using five parameters: background blood or clot, amount of cellular material, degree of cellular degeneration, degree of cellular trauma, and retention of appropriate architecture. The procedure with a...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Endobronchial ultrasound-guided; Transbronchial needle aspiration; Stylet; Cytology; Pathological diagnosis.
Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2017001000606
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