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| STRAUB,STEPHEN V; WAGNER II,LARRY E; BRUCE,JASON I.E; YULE,DAVID I. |
| Calcium release via intracellular Ca2+ release channels is a central event underpinning the generation of numerous, often divergent physiological processes. In electrically non-excitable cells, this Ca2+ release is brought about primarily through activation of inositol 1,4,5-trisphosphate receptors and typically takes the form of calcium oscillations. It is widely believed that information is carried in the temporal and spatial characteristics of these signals. Furthermore, stimulation of individual cells with different agonists can generate Ca2+ oscillations with dramatically different spatial and temporal characteristics. Thus, mechanisms must exist for the acute regulation of Ca2+ release such that agonist-specific Ca2+ signals can be generated. One... |
| Tipo: Journal article |
Palavras-chave: Inositol 1; 4; 5-trisphosphate receptor protein kinase A calcium signaling pancreatic acinar cells parotid acinar cells. |
| Ano: 2004 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602004000400013 |
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