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	Provedor de dados J. Venom. Anim. Toxins incl. Trop. Dis. (2) Autor Yunes,João Sarkis (2) Barros,Daniela Martí (1) Colvara,Wilson (1) Diehl,Felipe (1) Matthiensen,Alexandre (1) Ramos,Daniela Fernandes (1) Ramos,Patricia Baptista (1) Santos,Juliane Marques dos (1) Silva,Pedro Eduardo Almeida da (1) Trindade,Gilma Santos (1) Votto,Ana Paula Souza de (1) Mais... Palavra-chave Antimycobacterial agents (1) Aversive memory (1) Behavior (1) Cytotoxic activity (1) Drinking water (1) Microcystins (1) Mycobacteria (1) Rats (1) Saxitoxin (1) Spatial memory (1) Mais... Tipo do documento Info:eu-repo/semantics/article (2) Ano 2016 (1) 2015 (1) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Behavioral alterations induced by repeated saxitoxin exposure in drinking water J. Venom. Anim. Toxins incl. Trop. Dis. Diehl,Felipe; Ramos,Patricia Baptista; Santos,Juliane Marques dos; Barros,Daniela Martí; Yunes,João Sarkis. Abstract Background Blooms of the saxitoxin-producing cyanobacterium Cylindrospermopsis raciborskii have been contaminating drinking water reservoirs in Brazil for many years. Although acute effects of saxitoxin intoxication are well known, chronic deleterious outcomes caused by repeated saxitoxin exposure still require further investigation. The aim of the present work is to investigate the effects of consumption of drinking water contaminated with C. raciborskii for 30 days on learning and memory processes in rats. Methods The effects of saxitoxin (3 or 9 μg/L STX equivalents) or cyanobacteria on behavior was determined using the open field habituation task, elevated plus maze anxiety model task, inhibitory avoidance task, and referential Morris... Tipo: Info:eu-repo/semantics/article Palavras-chave: Saxitoxin; Drinking water; Behavior; Aversive memory; Spatial memory; Rats. Ano: 2016 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992016000100314 Antimycobacterial and cytotoxicity activity of microcystins J. Venom. Anim. Toxins incl. Trop. Dis. Ramos,Daniela Fernandes; Matthiensen,Alexandre; Colvara,Wilson; Votto,Ana Paula Souza de; Trindade,Gilma Santos; Silva,Pedro Eduardo Almeida da; Yunes,João Sarkis. Background The present work aimed to evaluate the antimycobacterial activity and cytotoxicity of Microcystis aeruginosa toxins, the MC-LR variant and purified extract of [D-Leu1] microcystin-LR. Methods The antimicrobial activity of M. aeruginosa extract and microcystin was evaluated by resazurin microtiter assay against Mycobacterium tuberculosis, M. terrae, M. chelonae and M. kansasii. The cytotoxicity assay was performed by trypan blue exclusion against the HTC cell line. Results Antimicrobial activity was observed in the hexanic extract of M. aeruginosa (RST 9501 strain) against M. tuberculosis, including sensitive and resistant strains with minimal inhibitory concentrations (MIC) between 1.93 μM and 0.06 μM. The high activity of M. aeruginosa hexanic... Tipo: Info:eu-repo/semantics/article Palavras-chave: Mycobacteria; Antimycobacterial agents; Cytotoxic activity; Microcystins. Ano: 2015 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992015000100315 Registros recuperados: 2 Primeira ... 1 ... Última

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