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| Zago,A.; Leão,R.M.; Carneiro-de-Oliveira,P.E.; Marin,M.T.; Cruz,F.C.; Planeta,C.S.. |
| Preclinical studies have shown that repeated stress experiences can result in an increase in the locomotor response to the subsequent administration of drugs of abuse, a phenomenon that has been termed behavioral cross-sensitization. Behavioral sensitization reflects neuroadaptive processes associated with drug addiction and drug-induced psychosis. Although cross-sensitization between stress- and drug-induced locomotor activity has been clearly demonstrated in adult rats, few studies have evaluated this phenomenon in adolescent rats. In the present study, we determined if the simultaneous exposure to stress and nicotine was capable of inducing behavioral sensitization to nicotine in adolescent and adult rats. To this end, adolescent (postnatal day (P)... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Cross-sensitization; Locomotor activity; Nicotine; Stress; Adolescence. |
| Ano: 2012 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2012000100006 |
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| Keller,R.; Zago,A.; Viana,M.C.; Bourboulia,D.; Desgranges,C.; Casseb,J.; Moura,W.V.; Dietze,R.; Collandre,H.. |
| The aims of the present study were to determine the prevalence of human herpesvirus type 8 (HHV-8) in HIV-positive Brazilian patients with (HIV+/KS+) and without Kaposi's sarcoma (HIV+/KS-) using PCR and immunofluorescence assays, to assess its association with KS disease, to evaluate the performance of these tests in detecting HHV-8 infection, and to investigate the association between anti-HHV-8 antibody titers, CD4 counts and staging of KS disease. Blood samples from 66 patients, 39 HIV+/KS+ and 27 HIV+/KS-, were analyzed for HHV-8 viremia in peripheral blood mononuclear cells by PCR and HHV-8 antigenemia for latent and lytic infection by immunofluorescence assay. Positive samples for latent nuclear HHV-8 antigen (LNA) antibodies were titrated out from... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: AIDS-related Kaposi's sarcoma; Human herpesvirus type 8; HHV-8; Brazil. |
| Ano: 2001 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2001000700007 |
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