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	Provedor de dados BJMBR (2) Autor Zhang,Q.Y. (2) Cao,J. (1) Ji,S.Q. (1) Li,Y.Y. (1) Tao,J.P. (1) Wang,Z.H. (1) Wei,M. (1) Yan,Y.Q. (1) Yu,F.X. (1) Zhu,W. (1) Mais... Palavra-chave Adipose tissue-derived stem cells (1) Angiogenesis (1) Angiopoietin (1) Invasion (1) Mast cell (1) Myocardial microvascular endothelial cells (1) Pancreatic cancer (1) Proliferation (1) SDF-1 (1) Tie-2 (1) Mais... Tipo do documento Info:eu-repo/semantics/article (2) Ano 2013 (2) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Adipose tissue-derived stem cells promote pancreatic cancer cell proliferation and invasion BJMBR Ji,S.Q.; Cao,J.; Zhang,Q.Y.; Li,Y.Y.; Yan,Y.Q.; Yu,F.X.. To explore the effects of adipose tissue-derived stem cells (ADSCs) on the proliferation and invasion of pancreatic cancer cells in vitroand the possible mechanism involved, ADSCs were cocultured with pancreatic cancer cells, and a cell counting kit (CCK-8) was used to detect the proliferation of pancreatic cancer cells. ELISA was used to determine the concentration of stromal cell-derived factor-1 (SDF-1) in the supernatants. RT-PCR was performed to detect the expression of the chemokine receptor CXCR4 in pancreatic cancer cells and ADSCs. An in vitro invasion assay was used to measure invasion of pancreatic cancer cells. SDF-1 was detected in the supernatants of ADSCs, but not in pancreatic cancer cells. Higher CXCR4 mRNA levels were detected in the... Tipo: Info:eu-repo/semantics/article Palavras-chave: Adipose tissue-derived stem cells; Pancreatic cancer; Proliferation; Invasion; SDF-1. Ano: 2013 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2013000900758 Stimulated mast cells promote maturation of myocardial microvascular endothelial cell neovessels by modulating the angiopoietin-Tie-2 signaling pathway BJMBR Wang,Z.H.; Zhu,W.; Tao,J.P.; Zhang,Q.Y.; Wei,M.. Angiopoietin (Ang)-1 and Ang-2 interact in angiogenesis to activate the Tie-2 receptor, which may be involved in new vessel maturation and regression. Mast cells (MCs) are also involved in formation of new blood vessels and angiogenesis. The present study was designed to test whether MCs can mediate angiogenesis in myocardial microvascular endothelial cells (MMVECs). Using a rat MMVEC and MC co-culture system, we observed that Ang-1 protein levels were very low even though its mRNA levels were increased by MCs. Interestingly, MCs were able to enhance migration, proliferation, and capillary-like tube formation, which were associated with suppressed Ang-2 protein expression, but not Tie-2 expression levels. These MCs induced effects that could be reversed by... Tipo: Info:eu-repo/semantics/article Palavras-chave: Myocardial microvascular endothelial cells; Mast cell; Angiogenesis; Angiopoietin; Tie-2. Ano: 2013 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2013001100920 Registros recuperados: 2 Primeira ... 1 ... Última

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