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	Provedor de dados BJMBR (1) Genet. Mol. Biol. (1) Autor Zhang,Ting (2) Bi,Xiao-xin (1) Chen,Rongfu (1) Huang,Jiankang (1) Huang,Ling (1) Jing,Mei-dong (1) Liu,Kangyong (1) Shen,Liwei (1) Sun,Xiaojiang (1) Yang,Jiajun (1) Zou,Yi (1) Mais... Palavra-chave 3-N-butylphthalide (1) Autophagy (1) Egretta garzetta (1) Mitochondrial genome (1) PC12 cells (1) Parkinson’s disease (1) Phylogenomics (1) Α-synuclein (1) Mais... Tipo do documento Info:eu-repo/semantics/article (2) Ano 2015 (1) 2012 (1) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Protection against neurotoxicity by an autophagic mechanism BJMBR Liu,Kangyong; Huang,Jiankang; Chen,Rongfu; Zhang,Ting; Shen,Liwei; Yang,Jiajun; Sun,Xiaojiang. The objective of the present study was to investigate the effects of 3-n-butylphthalide (NBP) on a 1-methyl-4-phenylpyridinium (MPP+)-induced cellular model of Parkinson’s disease (PD) and to illustrate the potential mechanism of autophagy in this process. For this purpose, rat PC12 pheochromocytoma cells were treated with MPP+ (1 mM) for 24 h following pretreatment with NBP (0.1 mM). Cell metabolic viability was determined by the MTT assay and cell ultrastructure was examined by transmission electron microscopy. The intracellular distribution and expression of α-synuclein and microtubule-associated protein light chain 3 (LC3) were detected by immunocytochemistry and Western blotting. Our results demonstrated that: 1) NBP prevented MPP+-induced... Tipo: Info:eu-repo/semantics/article Palavras-chave: 3-N-butylphthalide; Parkinson’s disease; Α-synuclein; PC12 cells; Autophagy. Ano: 2012 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2012000500004 The complete mitochondrial genome sequence of the little egret (Egretta garzetta) Genet. Mol. Biol. Zou,Yi; Jing,Mei-dong; Bi,Xiao-xin; Zhang,Ting; Huang,Ling. Many phylogenetic questions in the Ciconiiformes remain unresolved and complete mitogenome data are urgently needed for further molecular investigation. In this work, we determined the complete mitogenome sequence of the little egret (Egretta garzetta). The genome was 17,361 bp in length and the gene organization was typical of other avian mtDNA. In protein-coding genes (PCGs), a C insertion was found in ND3, and CO III and ND4 terminated with incomplete stop codons (T). tRNA-Val and tRNA-Ser (AGY) were unable to fold into canonical cloverleaf secondary structures because they had lost the DHU arms. Long repetitive sequences consisting of five types of tandem repeats were found at the 3′ end of Domain III in the control region. A phylogenetic analysis of... Tipo: Info:eu-repo/semantics/article Palavras-chave: Egretta garzetta; Mitochondrial genome; Phylogenomics. Ano: 2015 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572015000200162 Registros recuperados: 2 Primeira ... 1 ... Última

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