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| Wang,Jiaqi; Pan,Yixuan; Hu,Jiacheng; Ma,Qiang; Xu,Yi; Zhang,Yijian; Zhang,Fei; Liu,Yingbin. |
| Gallbladder cancer (GBC) is the most common malignancy in the biliary tract. Without effective treatment, its prognosis is notoriously poor. Tea polyphenols (TPs) have many pharmacological and health benefits, including antioxidant, anti-inflammatory, anti-tumor, anti-thrombotic, antibacterial, and vasodilatory properties. However, the anti-cancer effect of TPs in human gallbladder cancer has not yet been determined. Cell viability and colony formation assay were used to investigate the cell growth. Cell cycle and apoptosis were evaluated by flow cytometry analysis. Western blot assay was used to detect the expression of proteins related to cell cycle and apoptosis. Human tumor xenografts were used to examine the effect of TPs on gallbladder cancer cells... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Gallbladder cancer; Tea polyphenols; Apoptosis. |
| Ano: 2018 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2018000400614 |
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