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Effects of mercury intoxication on the response of horizontal cells of the retina of thraira fish (Hoplias malabaricus) BJMBR
Tanan,C.L.; Ventura,D.F.; de Souza,J.M.; Grotzner,S.R.; Mela,M.; Gouveia Jr.,A.; Oliveira-Ribeiro,C.A..
Methyl mercury (MeHg) is highly neurotoxic, affecting visual function in addition to other central nervous system functions. The effect of mercury intoxication on the amplitude of horizontal cell responses to light was studied in the retina of the fish Hoplias malabaricus. Intracellular responses were recorded from horizontal cells of fish previously intoxicated with MeHg by intraperitoneal injection (IP group) or by trophic exposure (T group). Only one retina per fish was used. The doses of MeHg chloride administered to the IP group were 0.01, 0.05, 0.1, 1.0, 2.0, and 6.0 mg/kg. The amplitudes of the horizontal cell responses were lower than control in individuals exposed to 0.01 (N = 4 retinas), 0.05 (N = 2 retinas) and 0.1 mg/kg (N = 1 retina), whereas...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Methyl mercury; Horizontal cells; Electrophysiology; Hoplias malabaricus; Retina.
Ano: 2006 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2006000700017
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