| The alteration of GABA levels has been involved in psychiatric disorders. Several studies have shown the pre-germinated brown rice (PGBR), that is a brown rice (BR) induced slight germination by soaking in the water, contains abundant of nutrients than BR especially GABA. However, there are few studies examining the effects of PGBR on brain functions. Therefore, the aim of the present study was to determine the effect of PGBR using Oryza sativa var. glutinosa on the depressive behavior in a rat model of depression using forced swimming test. Animals were divided into five groups; stress control group was treated with distilled water, fluoxetine group was treated with fluoxetine antidepressant and PGBR I, II and III groups were treated with PGBR 1, 3 and 5... |
