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Registros recuperados: 16 | |
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ALVARENGA,IVAN C.A.; PACHECO,FERNANDA V.; ALVARENGA,AMAURI A.; BERTOLUCCI,SUZAN K.V.; PINTO,JOSÉ EDUARDO B.P.. |
Abstract Yarrow (Achillea millefolium L., Asteraceae) is an important medicinal plant used worldwide for its medicinal properties such as the analgesic, antioxidant and anti-inflammatory ones. The aim of this study was to evaluate the growth and production of photosynthetic pigments and of volatile constituents of Achillea millefolium L. under different irrigation depths. The treatments were the application of 55, 110, 220, 440 and 880 mm of water for a period of 110 days. Data were submitted to polynomial regression analysis at 5% probability, while the volatile constituents were analyzed by standard deviation. Different irrigation depths provided quadratic growth responses being the highest dry matter production at the depth of 440 mm. The contents of... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Water stress; 1; 8 cineol; Chlorophyll; Terpenes. |
Ano: 2018 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652018000703901 |
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HERRERA,KARINA M.S.; FERREIRA,LORENA S.; BRAGA,ALYSSON V.; SOUZA,JULIANO P.; ANDRADE,JÉSSICA T.; SOARES,ADRIANA C.; SOARES,LUIS F.; CHAGAS,RAFAEL C.R.; FERREIRA,JAQUELINE M.S.. |
Abstract: Four novel Cr (III), Co (II) and Ni (II) complexes with 2-thiazoline-2-tiol derivative ligands were synthesized and characterized using elemental, physiochemical, and spectroscopy analytical methods. The results showed the formation of ligands coordinated by sulfur atoms of the C = S bond to the L1 ligand and by the sulfur atom of the C-S bond and/or nitrogen of the intra C-ring bond of the L2 ligand. The activity of the complexes against Gram-negative, Gram-positive bacteria and yeasts of clinical importance was evaluated by broth microdilution method. The best result was obtained to L2-Ni compound against E. cloacae (Minimal Inhibitory Concentration (MIC) = 62.5 µg/mL). Additionally, the compounds showed... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: 1; 2-bis-bis (2-thiazolin-2-isulfanyl) ethane antimicrobial activity hidrotris (2-mercaptothiazolyl) borate complexes. |
Ano: 2019 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652019000700803 |
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Freitas,Karine Moura de; Natali,Antônio José; Lunz,Wellington; Costa,Kyvia Lugate Cardoso; Leite,Rodrigo Paula; Dolder,Heidi; Matta,Sérgio Luis Pinto da. |
This study was undertaken to determine whether colon cancer (CC) and chronic swimming exercise alter rat testis. Eleven weeks old rats were distributed into control group (n=6) and the groups that were induced to develop CC by dimethylhydrazine injections (nEG, EG0, EG2 and EG4; n=10 each group). In the group nEG, the rats did not swim, whereas groups EG0, EG2 and EG4, underwent a swimming program with distinct loads (0, 2 and 4% of body mass, respectively) for 35 weeks. The morphometry, stereology and cell counts showed damage caused by the CC on the germ epithelium. These results were noteworthy since this was the first report to associate the CC with testicular damage. Swimming exercise had no significant role in reducing, or increasing the CC effects... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: 1; 2-dimethylhydrazine fertility reproduction spermatogenesis. |
Ano: 2013 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132013000400005 |
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Zhou,Y.; Wang,G.F.; Yang,L.; Liu,F.; Kang,J.Q.; Wang,R.L.; Gu,W.; Wang,C.Y.. |
Recent evidence indicates that a deficiency of 1,25-dihydroxyvitamin D3 (1,25[OH]2D3) may influence asthma pathogenesis; however, its roles in regulating specific molecular transcription mechanisms remain unclear. We aimed to investigate the effect of 1,25(OH)2D3 on the expression and enzyme activity of histone deacetylase 2 (HDAC2) and its synergistic effects with dexamethasone (Dx) in the inhibition of inflammatory cytokine secretion in a rat asthma model. Healthy Wistar rats were randomly divided into 6 groups: control, asthma, 1,25(OH)2D3 pretreatment, 1,25(OH)2D3 treatment, Dx... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: 1; 25-Dihydroxyvitamin D3 Asthma Acetylation Deacetylation Histone deacetylase 2 NF-κB. |
Ano: 2015 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2015000700654 |
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Iqbal,Javed; Rehman,Aziz-ur-; Abbasi,Muhammad Athar; Siddiqui,Sabahat Zahra; Rasool,Shahid; Ashraf,Muhammad; Iqbal,Ambar; Hamid,Sujhla; Chohan,Tahir Ali; Khalid,Hira; Laulloo,Sabina Jhaumeer; Shah,Syed Adnan Ali. |
We synthesized a series of compounds bearing pharmacologically important 1,3,4-oxadiazole and piperidine moieties. Spectral data analysis by 1H-NMR, 13C-NMR, IR and EI-MS was used to elucidate the structures of the synthesized molecules. Docking studies explained the different types of interaction of the compounds with amino acids, while bovine serum albumin (BSA) binding interactions showed their pharmacological effectiveness. Antibacterial screening of these compounds demonstrated moderate to strong activity against Salmonella typhi and Bacillus subtilis but only weak to moderate activity against the other three bacterial strains tested. Seven compounds were the most active members as... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: 1; 3; 4-Oxadiazole Acetylcholinesterase (AChE) inhibition Antibacterial activity Piperidine Sulfonamide Urease inhibition. |
Ano: 2020 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502020000100596 |
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Sattar,Almas; Aziz-ur-Rehman,; Abbasi,Muhammad Athar; Siddiqui,Sabahat Zahra; Rasool,Shahid; Ahmad,Irshad. |
ABSTRACT Keeping in mind the pharmacological importance of the 1,3,4-oxadiazole moiety, a series of new S-substituted derivatives, 5a-h, of 5-(1-(4-tosyl)piperidin-4-yl)-1,3,4-oxadiazol-2-thiol (3) were synthesized. The reaction of p-toluenesulfonyl chloride (a) and ethyl isonipecotate (b) produced ethyl 1-(4-tosyl)piperidin-4-carboxylate (1) which was further transformed into 1-(4-tosyl)piperidin-4-carbohydrazide (2) by hydrazine hydrate in methanol. Compound 2 was refluxed with CS2 in the presence of KOH to synthesize 5-( |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: 1; 3; 4-Oxadiazole/antibacterial activity. 1; 3; 4-Oxadiazole/enzyme inhibitory activity. Isonipecotate. Sulfonamide.. |
Ano: 2016 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502016000100009 |
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Lima,Rafaela Karin; Cardoso,Maria das Graças; Santos,Custódio Donizete dos; Moraes,Jair Campos; Néri,Danila Kelly Pereira; Nascimento,Evandro Afonso do. |
Nesta pesquisa, objetivou-se a obtenção e caracterização do óleo essencial de folhas da goiabeira Psidium guajava cv. Pedro Sato, e seus possíveis efeitos no comportamento da lagarta-do-cartucho do milho Spodoptera frugiperda. O óleo essencial foi obtido pela técnica "arraste a vapor d'água", utilizando-se de um aparelho de Clevenger modificado e submetido, posteriormente, à análise por cromatografia gasosa acoplada a um espectrômetro de massas CG-EM, a fim de investigar sua composição. Para a avaliação dos efeitos do óleo essencial no comportamento das lagartas de 1º ínstar foram testados quatro tratamentos, dois com o óleo essencial na concentração de 0,01% e 0,001%, diluídos em etanol/água |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: 1; 8-cineol repelência plantas inseticidas óleo essencial. |
Ano: 2009 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-70542009000700013 |
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Sattayasamitsathit,Supalak; Methacanon,Pawadee; Prasertsan,Poonsuk. |
The batch fermentation of 1,3-propanediol (1,3-PD) by Klebsiella pneumoniae SU6 at different crude glycerol concentration (40-100 g l-1), pH (6.5-7.5) and temperature (31-40ºC) combined with two-phase pH-controlled strategy was investigated. Effect of feeding rate (0.10-0.15 L h-1) was studied in fed-batch fermentation. In batch fermentation, the optimal condition was 60 g l-1 crude glycerol, pH control at 6.5 and cultivation temperature at 37ºC. The maximum 1,3-PD of 20 g l-1, the yield of 0.34 g |
Tipo: Journal article |
Palavras-chave: 1; 3-propanediol crude glycerol fed-batch fermentation Klebsiella pneumonia two-phase pH-control. |
Ano: 2011 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-34582011000600004 |
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Fargeas, Valérie; Baalouch, Myriam; Metay, Estelle; Baffreau, Jerôme; Menard, Dominique; Gosselin, Pascal; Berge, Jean-pascal; Barthomeuf, Chantal; Lebreton, Jacques. |
A simple and efficient methodology to introduce an 1,3-diketone motif from various aldehyde precursors in three steps with good overall yields is described using beta-ketosulphone 7 as masked equivalent of acetone. |
Tipo: Text |
Palavras-chave: 1; 3 diketones Alkylation Sulfones Aldehydes. |
Ano: 2004 |
URL: http://archimer.ifremer.fr/doc/2004/publication-829.pdf |
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Registros recuperados: 16 | |
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