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| OLIVEIRA,P. S. P.; CORRÊA,A. M. A.. |
| O efeito da serotonina e da monoablação do pedúnculo ocular na indução do desenvolvimento gonadal de Penaeus penicillatus (camarão do rabo vermelho) foi investigado. Fêmeas imaturas com peso médio de 20 g foram selecionadas e distribuídas de maneira aleatória em quatro grupos de 5 animais com uma réplica para cada grupo: grupo controle inicial (CI), sacrificado no 1º dia do experimento; grupo controle paralelo (GC), injetado com 0,05 ml de solução salina; grupo monoablado (GA), submetido à monoablação no dia 0 e injetado com 0,05 ml de solução salina logo após a monoablação e no 5º dia; grupo serotonina (GS), injetado com 0,05 ml de serotonina dissolvida em solução salina no dia 0 e 5º dia, numa dose total de 15 mg por grama de peso do animal (7,74 x 10-7... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Penaeus sp.; Serotonina; 5-HT; Reprodução; Maturação ovariana. |
| Ano: 1999 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0034-71081999000200017 |
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| Andreatini,R.; Blanchard,C.; Blanchard,R.; Brandão,M.L.; Carobrez,A.P.; Griebel,G.; Guimarães,F.S.; Handley,S.L.; Jenck,F.; Leite,J.R.; Rodgers,J.; Schenberg,L.C.; Da Cunha,C.; Graeff,F.G.. |
| This article is a transcription of an electronic symposium sponsored by the Brazilian Society of Neuroscience and Behavior (SBNeC). Invited researchers from the European Union, North America and Brazil discussed two issues on anxiety, namely whether panic is a very intense anxiety or something else, and what aspects of clinical anxiety are reproduced by animal models. Concerning the first issue, most participants agreed that generalized anxiety and panic disorder are different on the basis of clinical manifestations, drug response and animal models. Also, underlying brain structures, neurotransmitter modulation and hormonal changes seem to involve important differences. It is also common knowledge that existing animal models generate different types of... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Panic; Anxiety; Fear; Anxiolytics; 5-HT; Benzodiazepines; Serotonin; Amygdala; Periaqueductal gray matter; Animal models. |
| Ano: 2001 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2001000200001 |
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| Dai,S.Q.; Yu,L.P.; Shi,X.; Wu,H.; Shao,P.; Yin,G.Y.; Wei,Y.Z.. |
| The monoamine serotonin (5-hydroxytryptamine, 5-HT), a well-known neurotransmitter, also has important functions outside the central nervous system. The objective of this study was to investigate the role of 5-HT in the proliferation, differentiation, and function of osteoblasts in vitro. We treated rat primary calvarial osteoblasts with various concentrations of 5-HT (1 nM to 10 µM) and assessed the rate of osteoblast proliferation, expression levels of osteoblast-specific proteins and genes, and the ability to form mineralized nodules. Next, we detected which 5-HT receptor subtypes were expressed in rat osteoblasts at different stages of osteoblast differentiation. We found that 5-HT could inhibit osteoblast proliferation, differentiation, and... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Serotonin; Osteoblast; Proliferation; Differentiation; 5-HT receptors; 5-HT. |
| Ano: 2014 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2014000900759 |
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