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| Registros recuperados: 11 | |
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| Wolff,Fernando H.; Nhuch,Claudio; Cadore,Luciana P.; Glitz,Cristina L.; Lhullier,Francisco; Furlanetto,Tania W.. |
| Adrenocortical insufficiency is a serious complication of AIDS. Usually, integrity of the hypothalamo-pituitary-adrenal (HPA) axis in AIDS patients is assessed by measuring basal cortisol levels and cortisol response to 250 mug of ACTH. Recent studies suggest that a lower ACTH dose increases the sensitivity of the procedure. In the present study, we investigated the prevalence of adrenal hypofunction in AIDS patients using a low-dose ACTH test (1 mug), evaluated the clinical characteristics that might suggest this diagnosis, and the diseases and/or drugs that could be associated with it. We prospectively evaluated 63 very ill AIDS patients and 16 normal controls. A standard examination assessed the presence of signs and symptoms of adrenal insufficiency.... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: AIDS; Adrenal insufficiency; ACTH; Cortisol. |
| Ano: 2001 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702001000200002 |
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| Leal,A.M.O.; Moreira,A.C.. |
| Temporal organization is an important feature of biological systems and its main function is to facilitate adaptation of the organism to the environment. The daily variation of biological variables arises from an internal time-keeping system. The major action of the environment is to synchronize the internal clock to a period of exactly 24 h. The light-dark cycle, food ingestion, barometric pressure, acoustic stimuli, scents and social cues have been mentioned as synchronizers or" zeitgebers". The circadian rhythmicity of plasma corticosteroids has been well characterized in man and in rats and evidence has been accumulated showing daily rhythmicity at every level of the hypothalamic-pituitary-adrenal (HPA) axis. Studies of restricted feeding in rats are... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Feeding; Glucocorticoids; CRH; ACTH; Circadian rhythm. |
| Ano: 1997 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1997001200003 |
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| Genaro,G.; Schmidek,W.R.; Franci,C.R.. |
| Studies of behavior, endocrinology and physiology have described experiments in which animals housed in groups or in isolation were normally tested individually. The isolation of the animal from its group for testing is perhaps the most common situation used today in experimental procedures, i.e., there is no consideration of the acute stress which occurs when the animal is submitted to a situation different from that it is normally accustomed to, i.e., group living. In the present study, we used 90 male 120-day-old rats (Rattus norvegicus) divided into 5 groups of 18 animals, which were housed 3 per cage, in a total of 6 cages. The animals were tested individually or with their groups for exploratory behavior. Hormones were determined by radioimmunoassay... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Isolation; Group; Stress; Reproduction; ACTH; Luteinizing hormone; Corticosterone; Prolactin. |
| Ano: 2004 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2004000600008 |
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| Lotfi,C.F.P.; Lepique,A.P.; Forti,F.L.; Schwindt,T.T.; Eichler,C.B.; Santos,M.O.; Rebustini,I.T.; Hajj,G.N.M.; Juliano,L.; Armelin,H.A.. |
| This article reviews recent results of studies aiming to elucidate modes of integrating signals initiated in ACTH receptors and FGF2 receptors, within the network system of signal transduction found in Y1 adrenocortical cells. These modes of signal integration should be central to the mechanisms underlying the regulation of the G0->G1->S transition in the adrenal cell cycle. FGF2 elicits a strong mitogenic response in G0/G1-arrested Y1 adrenocortical cells, that includes a) rapid and transient activation of extracellular signal-regulated kinases-mitogen-activated protein kinases (ERK-MAPK) (2 to 10 min), b) transcription activation of c-fos, c-jun and c-myc genes (10 to 30 min), c) induction of c-Fos and c-Myc proteins by 1 h and cyclin D1 protein by... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: ACTH; FGF2; Signal transduction; MAP kinases; Early response genes. |
| Ano: 2000 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2000001000002 |
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| The existence of a circadian rhythm of atrial natriuretic peptide (ANP) in humans is controversial. We studied the plasma ANP response to isotonic blood volume expansion in the morning and in the afternoon and its relationship with adrenocorticotropic hormone (ACTH)-cortisol diurnal variation in seven normal subjects. Basal plasma ANP level was similar in the morning (19.6 ± 2.4 pg/ml) and in the afternoon (21.8 ± 4.8 pg/ml). The ANP peak obtained with saline infusion (0.9% NaCl, 12 ml/kg) in the morning (49.4 ± 8 pg/ml) did not differ from that obtained in the afternoon (60.3 ± 10.1 pg/ml). There was no correlation between the individual mean cortisol and ACTH levels and the ANP peak obtained with saline infusion. These data indicate no diurnal variation... |
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Palavras-chave: ANP; Diurnal variation; ACTH; Cortisol. |
| Ano: 1997 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1997000500008 |
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| Silva,Bárbara; Poleti,Mirele Daiana; Moncau,Cristina Tschorny; Rosa,Alessandra Fernandes; Silva,Saulo da Luz e; Balieiro,Júlio César de Carvalho. |
| O objetivo deste estudo foi avaliar características endócrinas (ACTH e cortisol plasmático), metabólicas (glicogênio e lactato muscular) e indicadoras de qualidade da carne em bovinos Nelore castrados e não castrados. Foram abatidos 130 animais (78 castrados e 52 não castrados), entre os anos de 2009 e 2011. Amostras de sangue foram coletadas, in vivo e post mortem (IV e PM), para mensurações endócrinas. Para os metabólitos, foram coletadas amostras do músculo Longissimus dorsi (LD). Para as análises físico-químicas, três bifes do músculo LD (entre a 10ª e 12ª costelas) foram maturados por um, sete e 14 dias. O pH e a temperatura dos animais foram mensurados a uma e 24 horas PM. As análises estatísticas foram realizadas por meio do procedimento de modelos... |
| Tipo: Info:eu-repo/semantics/other |
Palavras-chave: ACTH; Bovinos de corte; Cortisol; Glicogênio; Lactato. |
| Ano: 2014 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782014000500023 |
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| Registros recuperados: 11 | |
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