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| Mendes,L.C.; Ferreira,P.A.; Miotto,N.; Zanaga,L.; Gonçales,E.; Lazarini,M.S.; Gonçales Júnior,F.L.; Stucchi,R.S.B.; Vigani,A.G.. |
| Although long regarded as the gold standard for liver fibrosis staging in chronic hepatitis C (CHC), liver biopsy (LB) implies both the risk of an invasive procedure and significant variability. The aim of this study was to evaluate the diagnostic performance for transient elastography (TE) and aspartate aminotransferase to platelet index (APRI) used alone and in combination compared to liver biopsy and to analyze false positive/negative results. Patients with CHC, and no previous clinical diagnosis of cirrhosis were enrolled to undergo liver biopsy, TE and APRI. A total of 182 adult patients with a median age of 55 years and median body mass index of 26.71 kg/m2 were analyzed. On LB, 56% of patients had significant levels of fibrosis (METAVIR F≥2) and 28%... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Liver biopsy; Noninvasive tests; APRI; Transient elastography; Accuracy; False results. |
| Ano: 2016 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2016000900702 |
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