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	Provedor de dados 121 (1) 32 (1) 60 (1) 74 (1) Autor Cao,Xiyuan (1) El-Zaher,Asmaa Ahmed (1) Fouad,Marwa Ahmed (1) Hernández Lara, Blanca Isabel (1) Shi,Lixin (1) Sun,Shengkun (1) Wang,Chunyang (1) Youssef,Reem Baha-Aldeen (1) Zhang,Lei (1) Zhang,Xu (1) ed. por Cynthia J. Arnson (1) Mais... Palavra-chave AUC (4) Acetaminophen/pharmacokinetics (1) Area under curve (1) C max (1) COLOMBIA (1) CONFLICTOS (1) Chlorzoxazone/pharmacokinetics (1) Chromatography (1) DERECHOS HUMANOS (1) Diagnosis (1) Estadística (1) HPLC/methods (1) High Pressure Liquid/methods (1) Lycopene/ chemistry (1) Maestría (1) Metabolic clearance rate/drug effects (1) MicroRNA 378 (1) Paracetamol/pharmacokinetics (1) Patients (1) Rats/metabolism. (1) Mais... Tipo do documento Info:eu-repo/semantics/article (2) Text (1) Ano 2019 (1) 2017 (1) 2010 (1) 2005 (1) País Brazil (2) Ecuador (1) Mexico (1) Idioma Inglês (2) Espanhol (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 4 Primeira ... 1 ... Última Validated analytical study of the effect of Lycopene on the pharmacokinetics of Paracetamol and Chlorzoxazone in rats 60 Youssef,Reem Baha-Aldeen; Fouad,Marwa Ahmed; El-Zaher,Asmaa Ahmed. Lycopene was reported to influence some cytochrome P450 enzymes activity. The present study investigates the effect of lycopene on the pharmacokinetics of paracetamol and chlorzoxazone. Lycopene (20 mg/kg) was intra-peritoneally administered to two groups of rats for eight consecutive days and two other groups were given vehicle. On the eighth day, chlorzoxazone and paracetamol were separately intravenously administered to a lycopene group and a control group. Blood samples were collected at different time intervals, treated and analyzed using HPLC. The HPLC method used for paracetamol analysis was based on isocratic elution using a mobile phase consisting of water: methanol, (77:23 v/v) at a flow rate 1 mL min−1, Kromasil C18 column, and UV detection at... Tipo: Info:eu-repo/semantics/article Palavras-chave: Lycopene/ chemistry; Paracetamol/pharmacokinetics; Chlorzoxazone/pharmacokinetics; Acetaminophen/pharmacokinetics; AUC; Area under curve; Volume of distribution; Validation studies; Metabolic clearance rate/drug effects; HPLC/methods; Chromatography; High Pressure Liquid/methods; Rats/metabolism.. Ano: 2019 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502019000100540 The peace process in Colombia with the Autodefensas Unidas de Colombia - AUC 121 ed. por Cynthia J. Arnson. Tipo: Text Palavras-chave: DERECHOS HUMANOS; COLOMBIA; AUC; CONFLICTOS. Ano: 2005 URL: http://www.flacso.org.ec/biblio/shared/biblio_view.php?bibid=16687&tab=opac&oai:flacso.org.ec:16687 Bioequivalencia en casos de no normalidad 32 Hernández Lara, Blanca Isabel. La bioequivalencia es el procedimiento mediante el cual se decide si dos medicamentos uno de prueba y otro de referencia, se diferencian en un 20% por ciento o menos en términos de su velocidad y grado de absorción en los individuos. La prueba más usada para analizar este tipo de experimentos es la prueba de Shuirmann basada en la distribución normal. En este trabajo se propone una prueba basada en la transformación a rangos como una alternativa no parámetrica a la prueba de bioequivalencia de Shuirmann que mantenga el tamaño de prueba y una potencia aceptable en situaciones de no Normalidad. Se realizo un estudio de simulación para evaluar el comportamiento de la prueba supuesta comparándola con la prueba de Shuirmann y su alternativa no parámetrica... Palavras-chave: Transformación a rangos; AUC; C max; Transformation into ranges; Maestría; Estadística. Ano: 2010 URL: http://hdl.handle.net/10521/267 [RETRACTED ARTICLE]: Expression of serum microRNA-378 and its clinical significance in renal cell carcinoma 74 Shi,Lixin; Zhang,Lei; Wang,Chunyang; Sun,Shengkun; Cao,Xiyuan; Zhang,Xu. Abstract Studies have demonstrated that miRNA-378 is expressed in various malignant tumors. In the present study, we aimed to explore the expression of serum miRNA-378 and its clinical significance in renal cell carcinoma (RCC) patients. A total of 75 RCC patients, 63 renal cysts (RC) patients and 75 healthy controls were selected. The miRNA-378 level in RCC and RC groups was significantly higher than in healthy control group, with RCC group having the highest level. The miRNA-378 levels were significantly decreased within the same group after surgery. When compared with healthy controls, RC group had higher levels but not significantly (p > 0.05) while levels in RCC group were significantly higher (p < 0.05). miRNA-378 expression was correlated with... Tipo: Info:eu-repo/semantics/article Palavras-chave: Renal cell carcinoma; MicroRNA 378; Diagnosis; Patients; AUC. Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572017000300525 Registros recuperados: 4 Primeira ... 1 ... Última

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