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Registros recuperados: 22
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Association of plasmid typing to biotyping and antibiotyping in the characterization of outbreaks by Acinetobacter baumannii BABT
Tognim,Maria Cristina Bronharo; Gaziri,Luiz Carlos Jabur; Vidotto,Marilda Carlos; Perugini,Marcia Regina.
During an outbreak at an University Hospital, from April to September, in 1994, sixteen strains of Acinetobacter baumannii were isolated from patients and one strain from an enteral solution. We afterwards analyzed the outbreak by means of plasmid typing, antibiotic resistance typing and biotyping. Two main plasmid profiles were identified. Twelve strains belonged to biotype 2, and five to biotype 19. Susceptibility to amikacin and to carbenicillin allowed classification of the strains into two groups. The results show that association of those three typing methods allowed the differentiation of what was at first considered as a single outbreak into two apparently unrelated outbreaks.
Tipo: Info:eu-repo/semantics/article Palavras-chave: Acinetobacter baumannii; Outbreak; Plasmid/biotyping.
Ano: 1999 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89131999000100005
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Outbreak of resistant Acinetobacter baumannii: measures and proposal for prevention and control BJID
Romanelli,Roberta Maia de Castro; Jesus,Lenize Adriana de; Clemente,Wanessa Trindade; Lima,Stella Sala Soares; Rezende,Edna Maria; Coutinho,Rosane Luiza; Moreira,Ricardo Luiz Fontes; Neves,Francelli Aparecida Cordeiro; Brás,Nelma de Jesus.
Acinetobacter baumannii colonization and infection, frequent in Intensive Care Unit (ICU) patients, is commonly associated with high morbimortality. Several outbreaks due to multidrug-resistant (MDR) A. baumanii have been reported but few of them in Brazil. This study aimed to identify risk factors associated with colonization and infection by MDR and carbapenem-resistant A. baumannii strains isolated from patients admitted to the adult ICU at HC/UFMG. A case-control study was performed from January 2007 to June 2008. Cases were defined as patients colonized or infected by MDR/carbapenem-resistant A. baumannii, and controls were patients without MDR/carbapenem-resistant A. baumannii isolation, in a 1:2 proportion. For statistical analysis, due to changes...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Acinetobacter baumannii; Multidrug resistance; Carbapenem; Infection control; Outbreak.
Ano: 2009 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702009000500005
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Preliminary evaluation of adherence on abiotic and cellular surfaces of Acinetobacter baumannii strains isolated from catheter tips BJID
Costa,Gislaine Franco de Moura; Tognim,Maria Cristina Bronharo; Cardoso,Celso Luíz; Carrara-Marrone,Floristher Elaine; Garcia,Lourdes Botelho.
The cell surface hydrophobicity and adhesion to abiotic and cellular surfaces was tested in five clinical strains of Acinetobacter baumannii isolated from catheter tips. Biochemical and molecular characteristics of these strains were also studied. Hydrophobicity was characterized by a test for affinity to xylene. Adhesion to abiotic surfaces (polystyrene, formica, latex and glass) was evaluated in Petri plates using the stamp technique. Buccal epithelial cells were used for tests of adhesion to cellular surfaces. Adhesion to the catheter was evaluated by repeatedly rinsing the catheters and rolling them over nutrient agar. Molecular typing of the strains was done by the ERIC-PCR technique. The degree of hydrophobicity of the strains varied from hydrophobic...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Acinetobacter baumannii; Hydrophobicity; Adherence.
Ano: 2006 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702006000500009
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Mortality rate in patients with nosocomial Acinetobacter meningitis from a Brazilian hospital BJID
Tuon,Felipe Francisco; Penteado-Filho,Sergio R; Amarante,Diogo; Andrade,Marcio A; Borba,Luis A.
BACKGROUND: The mortality rate due to Acinetobacter baumannii nosocomial meningitis (ANM) is high. OBJECTIVE: The aim of this study was to evaluate the factors that have influence over the outcomes in ANM patients. METHODS: A retrospective analysis of 22 cases of ANM was conducted in a hospital with high incidence of multidrug resistance. RESULTS: The mean age of patients was 43 years (21 to 91) and 54.5% were male. All ANM cases occurred within 60 days of admission and the mean duration of illness was of 18.2 days. All cases were associated with previous neurosurgical procedures: elective surgery (27.2%), external shunt (54.4%) and emergency surgery due to trauma (18.1%). Imipenem resistance was observed in 40.9% of cases, but ampicillin/sulbactam...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Acinetobacter; Meningitis; Acinetobacter baumannii; Neurosurgery; Imipenem; Ampicillin/sulbactam.
Ano: 2010 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702010000500003
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Molecular epidemiology of Acinetobacter baumannii in central intensive care unit in Kosova teaching hospital BJID
Raka,Lul; Kalenc,Smilja; Bošnjak,Zrinka; Budimir,Ana; Katić,Stjepan; Šijak,Dubravko; Mulliqi-Osmani,Gjyle; Zoutman,Dick; Jaka,Arbëresha.
Infections caused by bacteria of genus Acinetobacter pose a significant health care challenge worldwide. Information on molecular epidemiological investigation of outbreaks caused by Acinetobacter species in Kosova is lacking. The present investigation was carried out to enlight molecular epidemiology of Acinetobacterbaumannii in the Central Intensive Care Unit (CICU) of a University hospital in Kosova using pulse field gel electrophoresis (PFGE). During March - July 2006, A. baumannii was isolated from 30 patients, of whom 22 were infected and 8 were colonised. Twenty patients had ventilator-associated pneumonia, one patient had meningitis, and two had coinfection with bloodstream infection and surgical site infection. The most common diagnoses upon...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Genotyping; Acinetobacter baumannii; Kosova; Intensive care unit.
Ano: 2009 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702009000600004
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Prevalence and molecular analysis of multidrug-resistant Acinetobacter baumannii in the extra-hospital environment in Mthatha, South Africa BJID
Anane A,Yaw; Apalata,Teke; Vasaikar,Sandeep; Okuthe,Grace Emily; Songca,Sandile.
ABSTRACT Introduction: The presence of Acinetobacter baumannii outside hospitals remains unclear. This study aimed to determine the prevalence of multidrug-resistance (MDR) A. baumannii in the extra-hospital environment in Mthatha, South Africa and to investigate the frequency of carbapenemase-encoding genes. Material and Methods: From August 2016 to July 2017 a total of 598 abattoir samples and 689 aquatic samples were collected and analyzed presumptively by cultural methods for the presence of A. baumannii using CHROMagar™ Acinetobacter medium. Species identification was performed by autoSCAN-4 (Dade Behring Inc., IL) and confirmed by the detection of their intrinsic blaOXA-51 gene. Confirmed MDR A. baumannii isolates were screened for the presence of...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Acinetobacter baumannii; Carbapenemase-encoding genes; Extra-hospital; Multidrug-resistance; ISAba1; IntI1.
Ano: 2019 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702019000600371
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Sulbactam-based therapy for Acinetobacter baumannii infection: a systematic review and meta-analysis BJID
Chu,Haiqing; Zhao,Lan; Wang,Minggui; Liu,Yang; Gui,Tao; Zhang,Jingbo.
BACKGROUND: A number of studies have reported on the effectiveness of sulbactam-based therapies for Acinetobacter baumannii infection; however, there is little evidence that sulbactam-based therapies are more or less effective than alternative therapies. Unfortunately, there is a distinct lack of high quality data (i.e., from randomized controlled trials) available on this issue. Therefore, we conducted a systematic review and meta-analysis comparing the efficacy of sulbactam-based and non-sulbactam-based regimens in the treatment of A. baumannii infection. METHODS: We searched PubMed, MEDLINE, Biomedical Central, Google Scholar, the China National Knowledge Infrastructure, the Cochrane library, and the Directory of Open Access using the terms "sulbactam...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Acinetobacter baumannii; Infection; Meta-analysis; Sulbactam; Systematic review.
Ano: 2013 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702013000400001
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Factors influencing survival in patients with multidrug-resistant Acinetobacter baumannii infection BJID
Prata-Rocha,Mariana Lima; Gontijo-Filho,Paulo Pinto; Melo,Geraldo Batista de.
Multidrug-resistant (MDR) Acinetobacter baumannii (Acb) is a rapidly emerging pathogen in healthcare settings. The aim of this study was to evaluate the predictors of poor outcome in patients with MDR Acb. This is the first report documenting factors influencing survival in patients with MDR Acb in this tertiary hospital. This study is a prospective of the hospital epidemiology database. A total of 73 patients with 84 Acb isolates were obtained between August 2009 and October 2010 in this hospital. In the present study, the 30-day mortality rate was 39.7%. Of 84 Acb isolates, 50 (59%) were MDR, nine (11%) were pan-resistant, and 25 (30%) were non-MDR. The non-MDR isolates were used as the control group. The factors significantly associated with multidrug...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Multidrug-resistant; Acinetobacter baumannii; Gram-negative bacteria.
Ano: 2012 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702012000300004
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Multidrug-resistant Acinetobacter baumannii clones persist on hospital inanimate surfaces BJID
Rocha,Igor Vasconcelos; Xavier,Danilo Elias; Almeida,Karoline Rissele Henrique de; Oliveira,Sibele Ribeiro de; Leal,Nilma Cintra.
ABSTRACT Acinetobacter baumannii is one of the most frequent Gram-negative opportunistic pathogens associated with hospital-acquired infection worldwide. We briefly describe A. baumannii isolates that were recovered from surrounding ICU bed surfaces, exhibiting multidrug resistance phenotype and belonging to some widely spread clonal complexes of clinical A. baumannii isolates.
Tipo: Info:eu-repo/semantics/other Palavras-chave: Acinetobacter baumannii; Hospital environment; ICU surface.
Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702018000500438
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Prevalence of carbapenem resistant Pseudomonas aeruginosa and Acinetobacter baumannii in high complexity hospital BJID
Baumgart,Ana Milda Karsten; Molinari,Marcelo André; Silveira,Alessandro Conrado de Oliveira.
Pseudomonas aeruginosa and Acinetobacter baumannii are Gram-negative bacilli that in the last decades have become prevalent agents of hospital infection due to high antimicrobial resistance developed by these microorganisms. The present study is a retrospective analysis of all positive cultures for these microorganisms in the period of January 2004 to December 2008. Resistance levels of A. baumannii and P. aeruginosa to carbapenems was high and showed a trend to increase during the period of study. In recent years the increasing incidence and resistance levels of A. baumannii and P. aeruginosa to the antimicrobials used for their treatment in the hospital setting underscores the relevance of infections caused by these bacteria. The selective pressure...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Acinetobacter baumannii; Pseudomonas aeruginosa; Drug resistance; Carbapenems; Hospital infection control program.
Ano: 2010 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702010000500002
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An outbreak of Acinetobacter baumannii septicemia in a neonatal intensive care unit of a university hospital in Brazil BJID
Brito,Denise von Dolinger de; Oliveira,Elias José; Abdallah,Vânia O. Steffen; Darini,Ana Lúcia da Costa; Gontijo Filho,Paulo P..
We studied an outbreak of two multi-drug resistant clones of Acinetobacter baumannii in the Neonatal Intensive Care Unit of the Uberlândia Federal University Hospital in Minas Gerais state, Brazil, and we analyzed the contribution of cross-transmission in the rise in infection rates. Eleven neonates who developed multi-drug resistant A. baumannii nosocomial infection were matched to 22 neonates who were admitted to the same unit and did not develop an infection during the outbreak period, in order to identify risk factors for infection. Three out of the 11 neonates died. Epidemiological investigation included molecular typing, using pulsed field gel electrophoresis. Prior to the outbreak, from December 2001 to March 2002, no case of infection by this...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Acinetobacter baumannii; Molecular epidemiology; Outbreak; Neonates.
Ano: 2005 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702005000400006
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Spread of multidrug-resistant Acinetobacter baumannii and Pseudomonas aeruginosa clones in patients with ventilator-associated pneumonia in an adult intensive care unit at a university hospital BJID
Royer,Sabrina; Faria,Ana Luiza Souza; Seki,Liliane Miyuki; Chagas,Thiago Pavoni Gomes; Campos,Paola Amaral de; Batistão,Deivid William da Fonseca; Asensi,Marise Dutra; Gontijo Filho,Paulo P.; Ribas,Rosineide Marques.
Background:In Brazil, ventilator-associated pneumonia (VAP) caused by carbapenem resis- tant Acinetobacter baumanniiand Pseudomonas aeruginosaisolates are associated with significant mortality, morbidity and costs. Studies on the clonal relatedness of these isolates could lay the foundation for effective infection prevention and control programs.Objectives: We sought to study the epidemiological and molecular characteristics of A. baumannii vs. P. aeruginosaVAP in an adult intensive care unit (ICU).Methods: It was conducted a cohort study of patients with VAP caused by carbapenem resistant A. baumanniiand P'. aeruginosaduring 14 months in an adult ICU. Genomic studies were used to investigate the clonal relatedness of carbapenem resistant OXA-23-producing...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Acinetobacter baumannii; Intensive care unit; Molecular epidemiology; Multidrug-resistant.
Ano: 2015 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702015000400350
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Clinical and microbiological characteristics of OXA-23- and OXA-143-producing Acinetobacter baumannii in ICU patients at a teaching hospital, Brazil BJID
Neves,Francelli Cordeiro; Clemente,Wanessa T.; Lincopan,Nilton; Paião,Isabela D.; Neves,Patrícia R.; Romanelli,Roberta M.; Lima,Stella S.S.; Paiva,Luciene F.; Mourão,Paulo Henrique O.; Nobre-Junior,Vandack A..
ABSTRACT Background: Carbapenem-resistant Acinetobacter baumannii (CRAb) is an important cause of nosocomial infections especially in intensive care units. This study aimed to assess clinical aspects and the genetic background of CRAb among ICU patients at a Brazilian teaching hospital. Methods: 56 critically ill patients colonized or infected by CRAb, during ICU stay, were prospectively assessed. Based on imipenem MIC ≥ 4 µg/mL, 28 CRAB strains were screened for the presence of genes encoding metallo-β-lactamases and OXA-type β-lactamases. The blaOXA-type genes were characterized by PCR using primers targeting ISAba-1 or -3. Genetic diversity of blaOXA-positive strains was determined by ERIC-PCR analysis. Results: Patient's mean age (±SD) was 61...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Acinetobacter baumannii; Carbapenem resistance; BlaOXA-23; BlaOXA-143.
Ano: 2016 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702016000600556
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Early dissemination of OXA-72-producing Acinetobacter baumannii strain in Colombia: a case report BJID
Saavedra,Sandra Yamile; Cayô,Rodrigo; Gales,Ana Cristina; Leal,Aura Lucia; Saavedra,Carlos Humberto.
Nosocomial infections caused by carbapenem-resistant Acinetobacter baumannii isolates have reached epidemic levels in past decades. Currently this microorganism is responsible for outbreaks of difficult eradication and with high mortality rates worldwide. We herein report a rare case of an OXA-72-producing A. baumannii isolate colonizing a 47-year-old male patient with peritonitis due to abdominal stab wound, four years earlier than the first report of this carbapenemase in Acinetobacter pittii in Colombia. Although OXA-72 presents a low prevalence compared with OXA-23, our study demonstrated that A. baumannii isolates carrying the blaOXA-72 gene were present in the hospital environment in Colombia and could act as a reservoir for further spread to other...
Tipo: Info:eu-repo/semantics/report Palavras-chave: Acinetobacter baumannii; Carbapenem-resistance; Oxacillinase; Colombia.
Ano: 2014 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702014000600678
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First occurrence of blaOXA-58 in Acinetobacter baumannii isolated from a clinical sample in Southern Brazil BJM
Gusatti,Carolina de Souza; Bertholdo,Lauren Martins; Otton,Letícia Muner; Marchetti,Desirée Padilha; Ferreira,Alessandra Einsfeld; Corção,Gertrudes.
This is the first report of an Acinetobacter baumannii from clinical origin carrying the blaOXA-58 gene in Brazil. The isolate included in this study was from a patient during an outbreak in Porto Alegre, RS, Southern Brazil, in 2007. It was resistant to most of the beta-lactams tested, it has also the blaOXA-65 gene and the ISAba1 sequence located upstream to both blaOXA genes detected and it has a MIC of imipenem of 64 μg/mL.
Tipo: Info:eu-repo/semantics/article Palavras-chave: BlaOXA-58; ISAba1; BlaOXA-65; Carbapenemases; Acinetobacter baumannii.
Ano: 2012 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822012000100027
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Production of humic substances through coal-solubilizing bacteria BJM
Valero,Nelson; Gómez,Liliana; Pantoja,Manuel; Ramírez,Ramiro.
In this paper, the production of humic substances (HS) through the bacterial solubilization of low rank coal (LRC) was evaluated. The evaluation was carried out by 19 bacterial strains isolated in microenvironments with high contents of coal wastes. The biotransformed LRC and the HS produced were quantified in vitro in a liquid growth medium. The humic acids (HA) obtained from the most active bacterial strain were characterized via elemental composition (C, H, N, O), IR analyses, and the E4/E6 ratio; they were then compared with the HA extracted chemically using NaOH. There was LRC biotransformation ranged from 25 to 37%, and HS production ranged from 127 to 3100 mg.L-1. More activity was detected in the isolated strains of Bacillus mycoides,...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Low rank coal; Microbacterium sp; Bacillus mycoides; Acinetobacter baumannii; Enterobacter aerogenes.
Ano: 2014 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822014000300021
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Bacteremia and meningitis caused by OXA-23-producing Acinetobacter baumannii – molecular characterization and susceptibility testing for alternative antibiotics BJM
Schuertz,Kamile Francine; Tuon,Felipe Francisco; Palmeiro,Jussara Kasuko; Conte,Danieli; Telles,João Paulo Marochi; Trevisoli,Lucas Eduardo; Dalla-Costa,Libera Maria.
Abstract Background: Carbapenem-resistant Acinetobacter baumannii infection is a concern in developing countries due to high incidence, few therapeutic options, and increasing costs. Objective: Characterize and analyze the antibiotic susceptibility patterns of carbapenem-resistant A. baumannii isolates and evaluate clinical data of meningitis and bacteremia caused by this microorganism. Methods: Twenty-six A. baumannii isolates from 23 patients were identified by MALDI-TOF and automated methods and genotyped using pulsed field genotyping electrophoresis. Clinical data and outcomes were evaluated. Susceptibility of isolates to colistin, tigecycline, meropenem, imipenem, and doxycycline was determined. Results: Mortality due to A. baumannii infections...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Acinetobacter baumannii; Oxacillinases; Carbapenem; Multidrug resistance; Doxycycline.
Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822018000500199
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Nosocomial outbreaks due to Pseudomonas aeruginosa and Acinetobacter baumannii in a Neonatal Intensive Care Unit (NICU) of the Uberlândia Federal University Hospital BJM
Brito,Denise Von Dolinger de; Oliveira,Elias Jose; Darini,Ana Lúcia da Costa; Abdallah,Vânia Olivetti Sttephen; Gontijo-Filho,Paulo Pinto.
The study documents the occurrence of two subsequent outbreaks in the NICU of HC-UFU, caused by epidemic strains of multiresistant Pseudomonas aeruginosa and Acinetobacter baumannii, that occurred between March/01 and September and between October/01 and March/02, respectively. The P. aeruginosa outbreak included seven neonates with conjunctivitis and three with bacteremia. A case-control study was conducted for the A. baumannii outbreak, with 11 and 22 neonates, respectively. The isolates of A. baumannii were resistant to gentamacin and ciprofloxacin. P. aeruginosa isolates were resistant to ampicillin/sulbactam gentamicin and ciprofloxacin. The hands of healthcare workers and environmental cultures were negative. The outbreak of P. aeruginosa resulted in...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Outbreak; Neonate; Acinetobacter baumannii; Pseudomonas aeruginosa.
Ano: 2003 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822003000500009
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Nickel biosorption by Acinetobacter baumannii and Pseudomonas aeruginosa isolated from industrial wastewater BJM
Rodríguez,Carlos E.; Quesada,Adolfo.
Nickel biosorption ability was evaluated in two bacterial strains: Acinetobacter baumannii UCR-2971 and Pseudomonas aeruginosa UCR-2957, resulting in greatest adsorption at pH 4.5 and a residence time of 100 minutes. Biosorption isotherms showed that the process follows the Langmuir model. The maximum adsorption rates (Nmax) were 8.8 and 5.7 mg·g-1 for A. baumannii and P. aeruginosa, respectively; however, affinity constants suggest that P. aeruginosa (K=1.28) has higher affinity for nickel than A. baumannii (K=0.68). It is suggested that both strains could be used for wastewater treatment, as long as the concentration of Ni2+ is within the range of mg·L-1.
Tipo: Info:eu-repo/semantics/article Palavras-chave: Biosorption; Nickel; Acinetobacter baumannii; Pseudomonas aeruginosa; Wastewater treatment.
Ano: 2006 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822006000400012
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Mobile genetic elements related to carbapenem resistance in Acinetobacter baumannii BJM
Pagano,Mariana; Martins,Andreza Francisco; Barth,Afonso Luis.
Abstract Acinetobacter baumannii is widely recognized as an important pathogen associated with nosocomial infections. The treatment of these infections is often difficult due to the acquisition of resistance genes. A. baumannii presents a high genetic plasticity which allows the accumulation of these resistance determinants leading to multidrug resistance. It is highlighted the importance of the horizontal transfer of resistance genes, through mobile genetic elements and its relationship with increased incidence of multidrug resistant A. baumannii in hospitals. Considering that resistance to carbapenems is very important from the clinical and epidemiological point of view, the aim of this article is to present an overview of the current knowledge about...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Acinetobacter baumannii; Antimicrobial resistance; Mobile genetic elements; Carbapenem resistance.
Ano: 2016 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822016000400785
Registros recuperados: 22
Primeira ... 12 ... Última
 

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