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| Araújo,Caliandra Pinto; Xavier,Flávia Caló de Aquino; Gurgel,Clarissa Araújo Silva; Ramos,Eduardo Antônio Gonçalves; Freitas,Valéria Souza; Schlaepfer-Sales,Caroline Brandi; Ramalho,Luciana Maria Pedreira; dos Santos,Jean Nunes. |
| The extracellular matrix (ECM) plays an important role in the regulation of biological events such as the development of cell migration, proliferation and differentiation. Chronic sun exposure causes changes present in the ECM of actinic cheilitis (AC), a premalignant lesion of the lower lip which helps to understand the carcinogenesis of the lip. This study aimed to investigate elastin, the main component of solar elastosis alternating current in an attempt to establish the relationship between this protein and ECM in epithelial dysplasia. Paraffin embedded tissue sections of the lesions of 35 cases of AC were analyzed by immunohistochemistry for elastin, and became the association with the degree of epithelial dysplasia and age. Highest scores of elastin... |
| Tipo: Journal article |
Palavras-chave: Matrix extracellular; Elastin; Immunohistochemistry; Actinic cheilitis. |
| Ano: 2012 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022012000200044 |
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