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Potential pathogenic role of aggregative- adhering Corynebacterium diphtheriae of different clonal groups in endocarditis BJMBR
Hirata Jr.,R.; Pereira,G.A.; Filardy,A.A.; Gomes,D.L.R.; Damasco,P.V.; Rosa,A.C.P.; Nagao,P.E.; Pimenta,F.P.; Mattos-Guaraldi,A.L..
Invasive diseases caused by Corynebacterium diphtheriae have been described increasingly. Several reports indicate the destructive feature of endocarditis attributable to nontoxigenic strains. However, few reports have dealt with the pathogenicity of invasive strains. The present investigation demonstrates a phenotypic trait that may be used to identify potentially invasive strains. The study also draws attention to clinical and microbiological aspects observed in 5 cases of endocarditis due to C. diphtheriae that occurred outside Europe. Four cases occurred in female school-age children (7-14 years) treated at different hospitals in Rio de Janeiro, Brazil. All patients developed other complications including septicemia, renal failure and/or arthritis....
Tipo: Info:eu-repo/semantics/article Palavras-chave: Aggregative adherence; Corynebacterium diphtheriae; Endocarditis; HEp-2 cells; Random amplified polymorphic DNA.
Ano: 2008 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2008001100007
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Expression of aggregative adherence to hela cells by Escherichia coli strains isolated from sick horses BJM
Liberatore,Ana Maria Alvim; Tomita,Sandra Kimie; Vieira,Mônica Aparecida Midolli; Toti Jr.,Cyro; Heckmaier,João; Gomes,Tânia Aparecida Tardelli.
The virulence attributes of 56 Escherichia coli strains isolated from sick horses (secretions of uterine cervices; gastrointestinal and lung fragments of necropsy; diarrheic feces, and tracheal washings) was examined by determining their adherence pattern to HeLa cells and searching for the presence of virulence genes of the various E. coli pathotypes. Two non-adherent strains presented astA, which encodes the enteroaggregative E. coli heat-stable toxin. Twenty-seven strains (48.2%) adhered to HeLa cells, 21 (77.8%) of which presented the aggregative adherence pattern (AA) that characterize the Enteroaggregative E. coli pathotype (EAEC). Nine of the strains presenting AA were isolated from secretions of uterine cervix, including one carrying virulence...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Horse; Escherichia coli; Aggregative adherence; Virulence.
Ano: 2007 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822007000100003
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