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| Pavão,Beatriz Philot; Demarque,Kelly Cristina; Batista,Marcos Meuser; Oliveira,Gabriel Melo de; Silva,Cristiane França da; Silva,Francisca Hildemagna Guedes da; Caputo,Luzia Fátima Gonçalves; Cascabulho,Cynthia Machado; Barcinski,Marcello André; Soeiro,Maria de Nazaré Correia. |
| Abstract Background: Autologous whole blood (AWB) administration is described as alternative/complementary medical practice widely employed in medical and veterinary therapy against infections, chronic pathologies and neoplasias. Our aim is to investigate in vivo biological effect of AWB using healthy murine models under the course of Trypanosoma cruzi acute infection. Methods: The first set of studies consisted of injecting different volumes of AWB and saline (SAL) into the posterior region of quadriceps muscle of healthy male Swiss mice under distinct therapeutic schemes evaluating: animal behavior, body and organ weight, hemogram, plasmatic biochemical markers for tissue damage and inflammatory cytokine levels and profile. To assess the impact on the... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Autologous blood; Alternative therapy; Mouse models; Trypanosoma cruzi. |
| Ano: 2018 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992018000100316 |
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