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| Mortara,Renato A.; Andreoli,Walter K.; Taniwaki,Noemi N.; Fernandes,Adriana B.; Silva,Claudio V. da; Fernandes,Maria Cecília D.C.; L'abbate,Carolina; Silva,Solange da. |
| Trypanosoma cruzi, the etiological agent of Chagas disease, occurs as different strains or isolates that may be grouped in two major phylogenetic lineages: T. cruzi I, associated with the sylvatic cycle and T. cruzi II, linked to the human disease. In the mammalian host the parasite has to invade cells and many studies implicated the flagellated trypomastigotes in this process. Several parasite surface components and some of host cell receptors with which they interact have been identified. Our work focused on how amastigotes, usually found growing in the cytoplasm, can invade mammalian cells with infectivities comparable to that of trypomastigotes. We found differences in cellular responses induced by amastigotes and trypomastigotes regarding... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Trypanosoma cruzi; Cellular invasion; Amastigotes; Trypomastigotes; Parasitophorous vacuole escape; Trafficking; Coxiella burnetii; Phylogenetic lineages. |
| Ano: 2005 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652005000100006 |
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