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| The present paper reviews work from our laboratories evaluating the importance of adrenal cortical hormones in acidification by proximal and cortical distal tubules. Proximal acidification was determined by stationary microperfusion, and measurement of bicarbonate reabsorption using luminal pH determination was performed with H+-ion-sensitive microelectrodes. Rats were adrenalectomized (ADX) 48 h before the experiments, and corticosteroids (aldosterone (A), corticosterone (B), and 18-OH corticosterone (18-OH-B)) were injected intramuscularly 100 and 40 min before the experiments. In ADX rats stationary pH increased significantly to 7.03 as compared to sham-operated rats (6.78). Bicarbonate reabsorption decreased from 2.65 ± 0.18 in... |
| Tipo: Info:eu-repo/semantics/other |
Palavras-chave: Aldosterone; Corticosterone; Bicarbonate reabsorption; Amiloride; Urine; PCO2. |
| Ano: 1997 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1997000400008 |
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| Havt,Alexandre; Assreuy,Ana Maria Sampaio; Nascimento,Nilberto Robson Falcão do; Fonteles,Manassés Claudino; Pereira,Lívia de Paula; Monteiro,Sandra Maria Nunes; Barbosa,Paulo Sergio Ferreira; Nascimento,Kyria Santiago do; Cavada,Benildo Sousa; Martins,Alice Maria Costa; Monteiro,Helena Serra Azul. |
| Lectins have been described as glycoproteins that reversibly and specifically bind to carbohydrates. Legume lectins isolated from the subtribe Diocleinae (Canavalia, Dioclea andCratylia) are structurally homologous with respect to their primary structures. The Diocleinae lectins of Canavalia brasiliensis, Dioclea guianensis andCanavalia ensiformis have been shown to distinctly alter physiological parameters in isolated rat kidneys. Thus, the aim of this study was to investigate the effect of Cratylia floribunda lectin (CFL) on renal hemodynamics and ion transport in rats. In isolated perfused kidneys, CFL (10 mg/mL, n=5) increased RPP, RVR and decreased %TK+, but did not change urinary flow, glomerular filtration rate, sodium or chloride tubular transport.... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Plant lectin; Amiloride; Cratylia floribunda/lectina/renal hemodynamics; Renal hemodynamics; Ion-transport. |
| Ano: 2015 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502015000300755 |
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