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Evaluation of antimicrobial activity and cell viability of Aloe vera sponges Electron. J. Biotechnol.
Gontijo,Sávio Morato de Lacerda; Gomes,Alinne Damásia Martins; Gala-García,Alfonso; Sinisterra,Rubén Dario; Cortés,Maria Esperanza.
Background: Aloe vera L., member of the Liliaceae family, has been shown to stimulate cell proliferation and contribute to healing and angiogenesis, has anti-bacterial, anti-fungal and anti-inflammatory activity. In addition, Aloe vera can be used as a support for drug transport. Our objective is to evaluate antimicrobial activity and cytotoxicity of sponges of Aloe vera L. for use as a carrying support of drugs. Results: In this work, sponge of free Aloe vera (AV) loaded with amoxicillin (AMX) or nystatin (NYS) at 1% w/w, were prepared and physico-chemically characterized via X-ray diffraction, Fourier Transform Infrared Spectroscopy and thermal analysis. Antimicrobial potency of AV sponge alone, loaded with AMX or NYS, against strains of Streptococcus...
Tipo: Journal article Palavras-chave: Amoxicillin; Cytotoxicity; Drug transport; Nystatin.
Ano: 2013 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-34582013000100002
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Antibacterial effect of crude methanol Carica papaya L. (papaya) extract and amoxicillin combination Plantas Medicinales
Bridge,Mwesigwa; Dominguez Montero,Genny; Betancourt Valladares,Miriela; Katawera,Victoria; Nkwangu,David; Oweta Noah,Joseph Openy.
Tipo: Journal article Palavras-chave: Additive interaction; Carica papaya; Amoxicillin; Minimum inhibitory concentration; Fractional inhibitory concentration index.
Ano: 2015 URL: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1028-47962015000400009
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Contrasting the crospovidones functionality as excipients for direct compression BJPS
Ramírez,Daniel García; Robles,Leopoldo Villafuerte.
Specific values of technological properties of excipients allow the establishment of numerical parameters to define and compare their functionality. This study investigates the functionality of Polyplasdones XL and XL10. Parameters studied included tablet disintegration profiles, compactibility profiles and powder flow. The results allowed the establishment of quantitative surrogate functionalities of technological performance, such as absolute number, and as a value relative to the known microcrystalline cellulose type 102. Moreover, the establishment of an explicit functionality to improve the technological performance of two diluents and a model drug was investigated, as was setting up of these functionalities, as quantitative values, to determine the...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Excipients/functionality; Polyplasdones XL/functionality; Polyplasdones XL10/functionality; Tablets/compactibility; Tablets/disintegration time; Tablets/powder flow; Amoxicillin; Magnesium stearate; Superdisintegrants.
Ano: 2015 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502015000100155
Registros recuperados: 3
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