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	Provedor de dados BJMBR (1) Autor Schteingart,D.E. (1) Palavra-chave Acyl-chloride metabolite (1) Angiogenic and chemotactic chemokines (1) Bromo-chloro and di-bromo analogs (1) Mitotane (1) Tipo do documento Info:eu-repo/semantics/article (1) Ano 2000 (1) País Brazil (1) Idioma Inglês (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 1 Primeira ... 1 ... Última Conventional and novel strategies in the treatment of adrenocortical cancer BJMBR Schteingart,D.E.. Adrenocortical carcinoma is a highly malignant neoplasm with an incidence of two per million people per year. Several treatment strategies have resulted in temporary or partial tumor regression but very few cases have attained long survival. Surgical resection of the primary tumor and metastases is most effective. Several chemotherapeutic protocols have been employed with variable success. Mitotane (o,p'-DDD) is an adrenalytic drug effective in inducing a tumor response in 33% of patients treated. Mitotane requires metabolic transformation for therapeutic action. Tumors may vary in their ability to metabolize mitotane and the ability of tumors to transform mitotane may predict the clinical response to the drug. Preliminary data show a possible correlation... Tipo: Info:eu-repo/semantics/article Palavras-chave: Mitotane; Acyl-chloride metabolite; Bromo-chloro and di-bromo analogs; Angiogenic and chemotactic chemokines. Ano: 2000 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2000001000009 Registros recuperados: 1 Primeira ... 1 ... Última

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