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Registros recuperados: 7
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Frequency of microorganisms isolated in patients with bacteremia in intensive care units in Colombia and their resistance profiles BJID
Cortes,Jorge Alberto; Leal,Aura Lucía; Montañez,Anita María; Buitrago,Giancarlo; Castillo,Juan Sebastián; Guzman,Lucy.
OBJECTIVE: The aim of this study was to describe the most frequently found bacterial microorganisms in bloodstream isolates taken from patients in intensive care units in Colombia and their resistance profiles. METHODS: This was a multicentre descriptive observational study that was carried out between January 2001 and June 2008 with laboratory data from 33 participating hospitals in a surveillance network. RESULTS: The most frequently found microorganisms were coagulase-negative Staphylococci 39.6%, Staphylococcus aureus 12.3%, Klebsiella pneumoniae 8.2%, Escherichia coli 5.7%, Acinetobacter baumannii, 4.0% and Pseudomonas aeruginosa 3.8%. Coagulase-negative Staphylococci registered greater than 70% oxacillin resistance rate. S. aureus presented a change...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Bacteremia; Intensive care unit; Drug resistance; Anti-bacterial agents; Colombia/epidemiology; Epidemiologic surveillance.
Ano: 2013 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702013000300007
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Vancomycin serum concentrations in pediatric oncologic/hematologic intensive care patients BJID
Silva,Dáfne Cardoso Bourguignon da; Seixas,Gláucia Toribio Finoti; Araujo,Orlei Ribeiro de; Arduini,Rodrigo Genaro; Carlesse,Fabianne Altruda de Moraes Costa; Petrilli,Antonio Sergio.
BACKGROUND: Usual treatment regimens with vancomycin often fail to provide adequate serum levels in patients with severe infections. METHODS: Retrospective analysis of vancomycin trough serum measurements. The following parameters were calculated by Bayesian analysis: vancomycin clearance, distribution volume, and peak estimated concentrations. The area under the concentration curve (AUC) (total daily dose/24 h clearance of vancomycin) was used to determine the effectiveness of treatment through the ratio of AUC/minimum inhibitory concentration (MIC) above 400, using MIC = 1 µg/mL, based on isolates of Staphylococci in cultures. RESULTS: Sixty-one vancomycin trough measurements were analyzed in 31 patients. AUC/MIC > 400 was obtained in 34 out of 61...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Immunosuppression; Drug resistance; Microbial; Staphylococcus; Anti-bacterial agents; Pharmacokinetics.
Ano: 2012 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702012000400009
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Characterization and sensitivity to antibiotics of bacteria isolated from the lower respiratory tract of ventilated patients hospitalized in intensive care units BJID
Medell,Manuel; Medell,Mariana; Martínez,Alicia; Valdés,Rodolfo.
OBJECTIVE: This observational study described the characterization of bacteria isolated from the lower respiratory tract of ventilated patients hospitalized in intensive care units. The demonstration of isolated microorganism resistance to antibiotics and a time-trend analysis of infection comparing a 48-month period were also other objectives. METHOD: Semi-quantitative assays of 1254 samples taken from 741 ventilated patients were performed, while pathogens were identified using the Enterotube II assay and VITEK 2 Compact equipment. Bacterial resistance to antibiotics was assessed by the Kirby-Bauer disc diffusion method and time-trend analysis of infection was based on data recorded by hospital microbiology laboratories. RESULTS: The most prevalent...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Anti-bacterial agents; Respiratory care units; Bronchopneumonia.
Ano: 2012 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702012000100008
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Intravenous azithromycin plus ceftriaxone followed by oral azithromycin for the treatment of inpatients with community-acquired pneumonia: an open-label, non-comparative multicenter trial BJID
Rubio,Fernando G.; Cunha,Clóvis A.; Lundgren,Fernando L.C.; Lima,Maria P.J.S.; Teixeira,Paulo J.Z.; Oliveira,Julio C.A.; Golin,Valdir; Mattos,Waldo L.L.D.; Mählmann,Herbert K.; Moreira,Edson D.; Jardim,Jose R.; Silva,Rodney L.F.; Silva,Patricia H.B..
Community-Acquired Pneumonia (CAP) is a major public health problem. In Brazil it has been estimated that 2,000,000 people are affected by CAP every year. Of those, 780,000 are admitted to hospital, and 30,000 have death as the outcome. This is an open-label, non-comparative study with the purpose of evaluating efficacy, safety, and tolerability levels of IV azithromycin (IVA) and IV ceftriaxone (IVC), followed by oral azithromycin (OA) for the treatment of inpatients with mild to severe CAP. Eighty-six patients (mean age 56.6 ± 19.8) were administered IVA (500mg/day) and IVC (1g/day) for 2 to 5 days, followed by AO (500mg/day) to complete a total of 10 days. At the end of treatment (EOT) and after 30 days (End of Study - EOS) the medication was evaluated...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Community acquired infections; Pneumonia; Anti-bacterial agents; Macrolide ketolides; Azithromycin.
Ano: 2008 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702008000300008
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Evaluation of different detection methods of biofilm formation in the clinical isolates BJID
Hassan,Afreenish; Usman,Javaid; Kaleem,Fatima; Omair,Maria; Khalid,Ali; Iqbal,Muhammad.
BACKGROUND: Microorganisms growing in a biofilm are associated with chronic and recurrent human infections and are highly resistant to antimicrobial agents. There are various methods to detect biofilm production like Tissue Culture Plate (TCP), Tube method (TM), Congo Red Agar method (CRA), bioluminescent assay, piezoelectric sensors, and fluorescent microscopic examination. OBJECTIVE: This study was conducted to compare three methods for the detection of biofilms. METHOD: The study was carried out at the Department of Microbiology, Army Medical College, National University of Sciences and Technology, Pakistan, from January 2010 to June 2010. A total of 110 clinical isolates were subjected to biofilm detection methods. Isolates were identified by standard...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Biofilms; Bacteria; Anti-bacterial agents.
Ano: 2011 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702011000400002
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Sex, drugs, bugs, and age: rational selection of empirical therapy for outpatient urinary tract infection in an era of extensive antimicrobial resistance BJID
Rocha,Jaime L.; Tuon,Felipe Francisco; Johnson,James R..
BACKGROUND: Optimal empirical therapy of urinary tract infection requires accurate knowledge of local susceptibility patterns, which may vary with organism and patient characteristics. METHODS: Among 9,798 consecutive, non-duplicate, community-source urine isolates from ambulatory patients > 13 years old, from clinical laboratory and an academic medical center in Curitiba, Brazil (May 1st to December 1st, 2009), susceptibility data for ampicillin, nitrofurantoin, trimethoprim-sulfamethoxazole, gentamicin, fluoroquinolones, and ceftriaxone/cefotaxime were compared with organism and patient gender and age. RESULTS: The female-to-male ratio decreased with age, from 28.1 (among 20-29 year-olds) to 3.3 (among > 80 year-olds). Overall, susceptibility...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Urinary tract infections; Anti-bacterial agents; Drug resistance bacterial; Fluoroquinolones; Escherichia coli.
Ano: 2012 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702012000200002
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Emergence of fluoroquinolone-resistant Neisseria gonorrhoeae in São Paulo, Brazil BJM
Belda Junior,Walter; Velho,Paulo Eduardo Neves Ferreira; Arnone,Marcelo; Fagundes,Luis Jorge.
Continued monitoring of antimicrobial resistance patterns is essential in order for Sexually Transmitted Diseases (STD) treatment to be effective. Gonococci isolates from 65 patients in São Paulo were submitted to susceptibility testing, and a decreased susceptibility or resistance to ciprofloxacin was observed in 8.7% of these patients, indicating that Neisseria gonorrhoeae fluoroquinolone resistance is emerging in Brazil.
Tipo: Info:eu-repo/semantics/article Palavras-chave: Anti-bacterial agents; Ciprofloxacin; Drug resistance; Neisseria gonorrhoeae.
Ano: 2007 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822007000200020
Registros recuperados: 7
Primeira ... 1 ... Última
 

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