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Estimated glomerular filtration rate and drug dose adjustment in patients in an intensive care unit in Brazil BJPS
Camargo,Marianne Silveira; Oliveira,Márcio Galvão; Mistro,Sostenes; Rocha,Izabel Cristina Pereira; Santos,Camila Neto; Castro,Caroline Tianeze de; Passos,Luiz Carlos Santana.
Objectives. This study sought to compare the estimated glomerular filtration rate and the indication of dose adjustment of antimicrobials when using Cockcroft-Gault or Modification of Diet in Renal Disease. Methods. A cross-sectional study was performed with patients admitted to the intensive care unit of a Brazilian general hospital. The glomerular filtration rate was calculated for patients on all days using the Cockcroft-Gault and Modification of Diet in Renal Disease equations. The difference in estimated glomerular filtration and the dose adjustment indication of antimicrobials were assessed. Results. A total of 631 patients were included in this study. The median estimated glomerular filtration was significantly higher when estimated using...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Intensive Care Units; Glomerular Filtration Rate; Anti-infective Agents; Renal Insufficiency.
Ano: 2020 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502020000100595
Registros recuperados: 1
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