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	Provedor de dados BJPS (1) International Journal of Morphology (1) Autor Dubey,Vinay (1) Ghosh,Asit Ranjan (1) Gicheru,M. M (1) Kiama,S. G (1) Makanya,A. N (1) Mutua,P. M (1) Sasikumar,Kandasamy (1) Mais... Palavra-chave Anti-proliferative (2) Anti-oxidant (1) Centella asiatica (1) Oleanolic acid (1) Respiratory epithelial cells (1) Vitis vinifera (1) Mais... Tipo do documento Info:eu-repo/semantics/article (1) Journal article (1) Ano 2020 (1) 2013 (1) País Brazil (1) Chile (1) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Oleanolic acid from black raisins, Vitis vinifera with antioxidant and antiproliferative potentials on HCT 116 colon cancer cell line BJPS Sasikumar,Kandasamy; Dubey,Vinay; Ghosh,Asit Ranjan. Vitis vinifera (black raisin) is commonly used in traditional medicine for the treatment of various ailments. In the present study, anti-oxidative and anti-cancer efficacy of oleanolic acid from ethyl acetate fraction of black raisins was evaluated and oleanolic acid was isolated without using of any chromatographic techniques and subjected to spectral assessment using UV-Vis spectrophotometer, 1H NMR, 13C NMR, MS and FT-IR for structural confirmation. Antiproliferative efficacy of oleanolic acid against human colon adenocarcinoma HCT-116 cells was assessed using cell viability assay. The minimum inhibitory concentration (IC50) was determined and found to be 40 µg/mL at 48h incubation. Furthermore, antioxidant property of oleanolic acid was analyzed using... Tipo: Info:eu-repo/semantics/article Palavras-chave: Vitis vinifera; Oleanolic acid; Anti-oxidant; Anti-proliferative. Ano: 2020 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502020000100502 Anti-Proliferative Activities of Centella Asiatica Extracts on Human Respiratory Epithelial Cells in vitro International Journal of Morphology Mutua,P. M; Gicheru,M. M; Makanya,A. N; Kiama,S. G. Centella asiatica or "pegaga" is well known for its ability in promoting wound healing. This study focused on the effect of Centella asiatica on the proliferation of human respiratory epithelial (RE) cells. RE cells were cultured using co-culture techniques until first passage (P1). Viability cell test by tryphan blue dye exclusion assay showed that there was high percentage of cell viability at both P0 (74%) and P1 (91.61%). Triplicate MTT assays were carried out with different concentrations of C. asiatica from 15.6 ppm, 31.3 ppm, 62.5 ppm, 125 ppm, 250 ppm, 500 ppm, 1000 ppm, until 2000 ppm. The higher the concentration of C. asiatica, the more inhibitory effect was seen. C. asiatica aqueous extract at concentration 1000 ppm and 2000 ppm demonstrated a... Tipo: Journal article Palavras-chave: Centella asiatica; Respiratory epithelial cells; Anti-proliferative. Ano: 2013 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022013000400028 Registros recuperados: 2 Primeira ... 1 ... Última

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