|
|
|
|
|
| Zeb,Anwar; Sadiq,Abdul; Ullah,Farhat; Ahmad,Sajjad; Ayaz,Muhammad. |
| BACKGROUND: Based on the ethnomedicinal uses and the effective outcomes of natural products in various diseases, this study was designed to evaluate Isodon rugosus as possible remedy in oxidative stress, alzheimer's and other neurodegenerative diseases. Acetylecholinestrase (AChE) and butyrylcholinesterase (BChE) inhibitory activities of crude methanolic extract (Ir.Cr), resultant fractions (n-hexane (Ir.Hex), chloroform (Ir.Cf), ethyl acetate (Ir.EtAc), aqueous (Ir.Aq)), flavonoids (Ir.Flv) and crude saponins (Ir.Sp) of I. rugosus were investigated using Ellman's spectrophotometric method. Antioxidant potential of I. rugosus was determined using DPPH, H2O2 and ABTS free radicals scavenging assays. Total phenolic and flavonoids contents of plant extracts... |
| Tipo: Journal article |
Palavras-chave: Anticholinesterase; Antioxidant; Flavonoids; Phenolics; Saponins; Isodon rugosus. |
| Ano: 2014 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602014000100070 |
| |
|
|
| Castro,R.R.T.; Porphirio,G.; Serra,S.M.; Nóbrega,A.C.L.. |
| Parasympathetic dysfunction is an independent risk factor in patients with coronary artery disease; thus, cholinergic stimulation is a potential therapeutic measure that may be protective by acting on ventricular repolarization. The purpose of the present study was to determine the effects of pyridostigmine bromide (PYR), a reversible anticholinesterase agent, on the electrocardiographic variables, particularly QTc interval, in patients with stable coronary artery disease. In a randomized double-blind crossover placebo-controlled study, simultaneous 12-lead electrocardiographic tracings were obtained at rest from 10 patients with exercise-induced myocardial ischemia before and 2 h after the oral administration of 45 mg PYR or placebo. PYR increased the RR... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Pyridostigmine; QTc interval; Stable angina; Anticholinesterase. |
| Ano: 2002 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2002000600008 |
| |
|
|
| Taşkın,Turgut; Gezmiş,Tuğba; Çam,Muhammet Emin; Taşkın,Duygu; Çelik,Berna Özbek; Şenkardeş,İsmail; Süzgeç-Selçuk,Sevda. |
| In Turkey, Helichrysum genus is represented by 26 taxa belonging to 20 species in Turkish flora of which 14 ones are endemic to Turkey. The aerial parts of Helichrysum plicatum subsp. plicatum are used kidney stones, kidney and stomach ailments. The extraction procedures and solvents are important step in processing of bioactive constituents from the plant materials. Therefore, the aim of this study was to evaluate in vitro antioxidant, antimicrobial, anti-urease, anticholinesterase and in vivo anti-inflammatory activities of Helichrysum plicatum subsp. plicatum different extracts. In addition, the phenolic characterization of the Soxhlet and maceration methanol extracts which showed significant antioxidant, anti-urease, antimicrobial, anti-inflammatory... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Helichrysum plicatum subsp; Plicatum; Anti-inflammatory; Anti-urease; Anticholinesterase; HPLC-DAD-MS. |
| Ano: 2020 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502020000100554 |
| |
|
|
|
